CRMP-1 Antibody (D-4): sc-365348
- CRMP-1 Antibody (D-4) is a mouse monoclonal IgG1 κ CRMP-1 antibody, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 497-523 near the C-terminus of CRMP-1 of human origin
- CRMP-1 Antibody (D-4) is recommended for detection of CRMP-1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and canine, bovine and porcine
- Anti-CRMP-1 Antibody (D-4) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRMP-1 Antibody (D-4) for WB applications. These reagents are now offered in bundles with CRMP-1 Antibody (D-4) (see ordering information below).
QUICK LINKS
CRMP-1 Antibody (D-4) is a mouse monoclonal IgG1 kappa light chain antibody that detects CRMP-1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRMP-1 (D-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Collapsin response mediator proteins (CRMPs), such as CRMP-1, play a crucial role in neuronal signaling, particularly in response to the axon guidance molecule Semaphorin 3A (SEMA3A). CRMP-1 is involved in regulating neuronal development and plasticity, while also contributing to invasion and metastasis in cancer biology. CRMP-1 primarily localizes in the cytoplasm and facilitates the transport of signaling molecules and structural components necessary for axon growth and guidance in neuronal cells. Alterations in CRMP-1 expression or localization can significantly impact neurodevelopmental disorders and cancer progression.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CRMP-1 Antibody (D-4) References:
- Genomic organization and localization of the human CRMP-1 gene. | Torres, R. and Polymeropoulos, MH. 1998. DNA Res. 5: 393-5. PMID: 10048489
- Collapsin response mediator protein-1: a novel invasion-suppressor gene. | Shih, JY., et al. 2003. Clin Exp Metastasis. 20: 69-76. PMID: 12650609
- Subcellular localization of collapsin response mediator proteins to lipid rafts. | Rosslenbroich, V., et al. 2003. Biochem Biophys Res Commun. 305: 392-9. PMID: 12745088
- Involvement of collapsin response mediator proteins in the neurite extension induced by neurotrophins in dorsal root ganglion neurons. | Quach, TT., et al. 2004. Mol Cell Neurosci. 25: 433-43. PMID: 15033171
- Haplotype and linkage disequilibrium analysis of the CRMP1 and EVC genes. | Sivakumaran, TA. and Lesperance, MM. 2004. Int J Mol Med. 14: 903-7. PMID: 15492864
- Downregulation of metastasis suppressor genes in malignant pheochromocytoma. | Ohta, S., et al. 2005. Int J Cancer. 114: 139-43. PMID: 15523699
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRMP-1 Antibody (D-4) | sc-365348 | 200 µg/ml | $316.00 | |||
CRMP-1 Antibody (D-4): m-IgG Fc BP-HRP Bundle | sc-529355 | 200 µg Ab; 10 µg BP | $354.00 | |||
CRMP-1 Antibody (D-4): m-IgGκ BP-HRP Bundle | sc-522215 | 200 µg Ab, 40 µg BP | $354.00 | |||
CRMP-1 Antibody (D-4): m-IgG1 BP-HRP Bundle | sc-543475 | 200 µg Ab; 20 µg BP | $354.00 | |||
CRMP-1 Antibody (D-4) AC | sc-365348 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CRMP-1 Antibody (D-4) HRP | sc-365348 HRP | 200 µg/ml | $316.00 | |||
CRMP-1 Antibody (D-4) FITC | sc-365348 FITC | 200 µg/ml | $330.00 | |||
CRMP-1 Antibody (D-4) PE | sc-365348 PE | 200 µg/ml | $343.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 488 | sc-365348 AF488 | 200 µg/ml | $357.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 546 | sc-365348 AF546 | 200 µg/ml | $357.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 594 | sc-365348 AF594 | 200 µg/ml | $357.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 647 | sc-365348 AF647 | 200 µg/ml | $357.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 680 | sc-365348 AF680 | 200 µg/ml | $357.00 | |||
CRMP-1 Antibody (D-4) Alexa Fluor® 790 | sc-365348 AF790 | 200 µg/ml | $357.00 | |||
CRMP-1 (D-4) Neutralizing Peptide | sc-365348 P | 100 µg/0.5 ml | $68.00 |