CRBP III Antibody (A-12): sc-390258
- CRBP III Antibody (A-12) is a mouse monoclonal IgG1 κ CRBP III antibody provided at 200 µg/ml
- raised against amino acids 1-135 representing full length CRBP III of human origin
- CRBP III Antibody (A-12) is recommended for detection of CRBP III of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CRBP III Antibody (A-12) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of CRBP III (A-12): sc-390258.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CRBP III Antibody (A-12) for WB applications. These reagents are now offered in bundles with CRBP III Antibody (A-12) (see ordering information below).
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CRBP III Antibody (A-12) is a mouse monoclonal IgG1 kappa light chain antibody that detects CRBP III protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRBP III (A-12) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. The cellular retinol-binding proteins, which include CRBP I, II, III, and IV, are crucial for the intracellular transport and metabolism of retinol, the alcohol form of vitamin A. CRBP III plays a significant role in the cytoplasmic transport of retinol, ensuring this vital nutrient is effectively delivered to the enzymes responsible for its conversion into retinoic acid, a key molecule involved in gene expression, cell differentiation, and embryonic development. Proper functioning of CRBP III is essential for maintaining retinol homeostasis within cells, and dysregulation can lead to various developmental and metabolic disorders. Understanding CRBP III structure and function is important for elucidating its role in vitamin A metabolism and implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CRBP III Antibody (A-12) References:
- Regulation of vitamin A metabolism-related gene expression. | Takase, S., et al. 2000. Br J Nutr. 84 Suppl 2: S217-21. PMID: 11242473
- Identification, retinoid binding, and x-ray analysis of a human retinol-binding protein. | Folli, C., et al. 2001. Proc Natl Acad Sci U S A. 98: 3710-5. PMID: 11274389
- Regulation of alpha-smooth muscle actin and CRBP-1 expression by retinoic acid and TGF-beta in cultured fibroblasts. | Xu, G., et al. 2001. J Cell Physiol. 187: 315-25. PMID: 11319755
- Quantitation of cellular retinol-binding protein in human organs. | Ong, DE. and Page, DL. 1986. Am J Clin Nutr. 44: 425-30. PMID: 3751963
- Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with all-trans-retinol. | Cowan, SW., et al. 1993. J Mol Biol. 230: 1225-46. PMID: 7683727
- [Cellular retinoid-binding proteins]. | Okuno, M., et al. 1993. Nihon Rinsho. 51: 879-85. PMID: 8387121
- Crystal structures of holo and apo-cellular retinol-binding protein II. | Winter, NS., et al. 1993. J Mol Biol. 230: 1247-59. PMID: 8487303
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CRBP III Antibody (A-12) | sc-390258 | 200 µg/ml | $316.00 | |||
CRBP III Antibody (A-12): m-IgG Fc BP-HRP Bundle | sc-530110 | 200 µg Ab; 10 µg BP | $354.00 | |||
CRBP III Antibody (A-12): m-IgGκ BP-HRP Bundle | sc-523469 | 200 µg Ab, 40 µg BP | $354.00 | |||
CRBP III Antibody (A-12): m-IgG1 BP-HRP Bundle | sc-543873 | 200 µg Ab; 20 µg BP | $354.00 | |||
CRBP III Antibody (A-12) AC | sc-390258 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CRBP III Antibody (A-12) HRP | sc-390258 HRP | 200 µg/ml | $316.00 | |||
CRBP III Antibody (A-12) FITC | sc-390258 FITC | 200 µg/ml | $330.00 | |||
CRBP III Antibody (A-12) PE | sc-390258 PE | 200 µg/ml | $343.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 488 | sc-390258 AF488 | 200 µg/ml | $357.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 546 | sc-390258 AF546 | 200 µg/ml | $357.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 594 | sc-390258 AF594 | 200 µg/ml | $357.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 647 | sc-390258 AF647 | 200 µg/ml | $357.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 680 | sc-390258 AF680 | 200 µg/ml | $357.00 | |||
CRBP III Antibody (A-12) Alexa Fluor® 790 | sc-390258 AF790 | 200 µg/ml | $357.00 |