CRALBP Antibody (D-10): sc-48354

CRALBP Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects CRALBP in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CRALBP, or cellular retinaldehyde-binding protein, plays a crucial role in the visual cycle by binding to 11-cis-retinol and facilitating its transport within the retina, which is essential for the regeneration of visual pigments in photoreceptor cells. CRALBP is predominantly located in the retinal pigment epithelium and Müller cells, where CRALBP helps maintain the supply of chromophore necessary for phototransduction. Proper functioning of CRALBP is vital, as mutations in the CRALBP gene can lead to significant retinal pathologies and impaired dark adaptation, highlighting CRALBP′s importance in visual health. Anti-CRALBP antibody (D-10) is an invaluable tool for researchers studying the visual cycle and related retinal disorders, providing insights into the molecular mechanisms underlying vision and potential therapeutic targets for retinal diseases.

The preferred CRALBP antibody is CRALBP Antibody (B2): sc-59487.