Date published: 2025-10-19

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COPZ1 Antibody (F-11): sc-398220

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Datasheets
  • COPZ1 Antibody (F-11) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 128-159 near the C-terminus of COPZ1 of human origin
  • recommended for detection of COPZ1 of mouse, rat and human origin by WB, IP, IF and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
  • m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for COPZ1 Antibody (F-11) for WB applications. These reagents are now offered in bundles with COPZ1 Antibody (F-11) (see ordering information below).

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    COPZ1 Antibody (F-11) is a mouse monoclonal IgG2b antibody that detects COPZ1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COPZ1, a crucial component of the coatomer protein complex I (COPI), plays a vital role in membrane and vesicular trafficking within the early secretory pathway, facilitating retrograde transport from the Golgi apparatus back to the endoplasmic reticulum (ER) as well as intra-Golgi transport. The structure of COPZ1 is particularly important as COPZ1 forms part of the heptameric coatomer complex, which is essential for the assembly of COPI-coated vesicles. This complex is composed of two subcomplexes: one includes the β-, γ-, δ-, and ζ-COP subunits, while the other consists of α-COP, β′-COP, and ε-COP subunits. The proper functioning of COPZ1 and associated proteins is critical for maintaining cellular homeostasis and ensuring efficient protein sorting and trafficking, which are fundamental processes for cell survival and function. Anti-COPZ1 antibody (F-11) enables researchers to gain insights into the dynamics of vesicular transport and the underlying mechanisms of various cellular processes, making anti-COPZ1 antibody (F-11) an invaluable tool for studies in cell biology and related fields.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    COPZ1 Antibody (F-11)

    sc-398220
    200 µg/ml
    $316.00

    COPZ1 Antibody (F-11): m-IgGκ BP-HRP Bundle

    sc-536003
    200 µg Ab; 40 µg BP
    $354.00

    COPZ1 Antibody (F-11): m-IgG2b BP-HRP Bundle

    sc-549503
    200 µg Ab; 10 µg BP
    $354.00

    COPZ1 (F-11) Neutralizing Peptide

    sc-398220 P
    100 µg/0.5 ml
    $68.00

    What application is the blocking peptide sc-398220 P appropriate for?

    Asked by: Professor Griffin
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-02-28
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    Rated 5 out of 5 by from Very good Western blot data of COPZ1 expressionVery good Western blot data of COPZ1 expression in COS, K-562 and Jurkat whole cell lysates. -SCBT QC
    Date published: 2014-01-13
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    COPZ1 Antibody (F-11) is rated 5.0 out of 5 by 1.
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