COPB Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects COPB in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COPB, also known as β-COP, plays a crucial role in membrane and vesicular trafficking within the early secretory pathway, specifically as a marker protein for pre-Golgi intermediates, including vesicular tubular clusters (VTCs). COPB functions as a major component of the coat of non-Clathrin-coated vesicles, which are essential for mediating membrane traffic through the Golgi complex. This trafficking is vital for proper sorting and delivery of proteins and lipids, ensuring cellular processes function efficiently. Additionally, COPB interacts with various proteins, such as GIV (Gα i/s interacting protein) and β′-COP (COPP), which further underscores COPB′s significance in dynamic regulation of vesicular transport. Anti-COPB antibody (D-9) serves as an invaluable tool for researchers studying cellular transport mechanisms and their implications in health and disease.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COPB Antibody (D-9) | sc-165975 | 200 µg/ml | $316.00 | |||
COPB Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-537426 | 200 µg Ab; 10 µg BP | $354.00 | |||
COPB Antibody (D-9): m-IgGκ BP-HRP Bundle | sc-534684 | 200 µg Ab; 40 µg BP | $354.00 |