COMMD8 Antibody (D-7): sc-514188
- COMMD8 Antibody (D-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 33-56 within an internal region of COMMD8 of mouse origin
- recommended for detection of COMMD8 of mouse and rat origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for COMMD8 Antibody (D-7) for WB applications. These reagents are now offered in bundles with COMMD8 Antibody (D-7) (see ordering information below).
COMMD8 Antibody (D-7) is a mouse monoclonal IgG2a antibody that detects COMM domain-containing protein 8 (COMMD8) in mouse and rat samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). COMMD8, a member of the highly conserved COMMD protein family, consists of 183 amino acids and is predominantly expressed in the thyroid, where COMMD8 plays a crucial role in cellular processes. Notably, COMMD8 is involved in the regulation of the NFκB signaling pathway, which is essential for controlling immune responses and inflammation. By modulating this pathway, COMMD8 contributes to the maintenance of cellular homeostasis and the prevention of excessive inflammatory responses, highlighting COMMD8′s importance in both health and disease. Additionally, COMMD8 has been implicated in copper homeostasis and may influence the function of epithelial sodium channels, further underscoring COMMD8′s multifaceted role in cellular physiology. The unique structure of COMMD8, characterized by its COMM domain, facilitates protein-protein interactions that are vital for its regulatory functions, making anti-COMMD8 antibody (D-7) an invaluable tool for researchers studying these critical biological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COMMD8 Antibody (D-7) | sc-514188 | 200 µg/ml | $322.00 | |||
COMMD8 Antibody (D-7): m-IgG Fc BP-HRP Bundle | sc-538601 | 200 µg Ab; 10 µg BP | $361.00 | |||
COMMD8 Antibody (D-7): m-IgGκ BP-HRP Bundle | sc-536245 | 200 µg Ab; 40 µg BP | $361.00 | |||
COMMD8 Antibody (D-7): m-IgG2a BP-HRP Bundle | sc-548350 | 200 µg Ab; 10 µg BP | $361.00 | |||
COMMD8 (D-7) Neutralizing Peptide | sc-514188 P | 100 µg/0.5 ml | $69.00 |