COL1A2 Antibody (H-9): sc-376350

COL1A2 Antibody (H-9) is a mouse monoclonal IgG1 kappa light chain antibody designed to recognize Collagen α2 Type I, also known as COL1A2 or Collagen type I alpha2 chain. anti-COL1A2 antibody (H-9) is raised against amino acids 1021-1090 within an internal region of COL1A2, ensuring precise targeting and high affinity for its epitope. Collagen α2 Type I is a crucial component of the extracellular matrix, forming a triple helix structure that provides remarkable tensile strength and structural integrity to connective tissues such as tendons, skin, bone, and cartilage. The robust triple helix formation and ability of COL1A2 to self-assemble into fibrils are essential for maintaining the mechanical properties and resilience of these tissues. COL1A2 monoclonal antibody (H-9) effectively detects Collagen α2 Type I in multiple species including mouse, rat, human, canine, bovine, and porcine through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). The broad species reactivity makes COL1A2 (H-9) antibody an invaluable tool for comparative studies and research involving various animal models. Additionally, the structural role of COL1A2 in cell adhesion and tissue architecture underscores its importance in both normal physiological processes and pathological conditions such as fibrosis and connective tissue disorders. Available in both non-conjugated and multiple conjugated forms, including horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® variants, COL1A2 (H-9) monoclonal antibody offers flexibility for diverse experimental setups. By targeting essential structural domains of COL1A2, anti-COL1A2 antibody (H-9) facilitates detailed investigations into molecular mechanisms governing tissue integrity and repair.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-COL1A2 Antibody (H-9) has 12 citations in a variety of scientific publications.

Primary antibodies like Anti-COL1A2 Antibody (H-9) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

COL1A2 Antibody (H-9) Specifications

Alternate Product Name: collagen 1 type COL1A2

Product Clone Name: H-9

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1021-1090

Epitope Target: Collagen α2 Type I

Epitope Species: human

Product Reactivity/Detection: Collagen α2 Type I

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine, bovine and porcine

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 12 citations in various scientific publications

Available Conjugates/Forms for COL1A2 Antibody (H-9): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred Pro-COL1A2 antibody is Pro-COL1A2 Antibody (D-6): sc-166572.