COL1A2 Antibody (E-6): sc-393573
- COL1A2 Antibody (E-6) is a mouse monoclonal IgG1 λ COL1A2 antibody, cited in 19 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 1064-1093 at the C-terminus of Collagen α2 Type I of mouse origin
- COL1A2 Antibody (E-6) is recommended for detection of Collagen α2 Type I of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-COL1A2 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for COL1A2 Antibody (E-6) for WB and IHC(P) applications. This reagent is now offered in a bundle with COL1A2 Antibody (E-6) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
COL1A2 Antibody (E-6) is a mouse monoclonal IgG1 lambda light chain antibody designed to recognize Collagen α2 Type I, also known as COL1A2 or Collagen type I alpha2 chain. COL1A2 monoclonal antibody (E-6) targets a precise epitope mapping between amino acids 1064-1093 at the C-terminus of the COL1A2 protein, ensuring robust and reliable detection across various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Collagen α2 Type I is a crucial component of the extracellular matrix, playing a vital role in maintaining the structural integrity and tensile strength of connective tissues such as tendons, skin, bone, and cartilage. COL1A2 undergoes significant post-translational modifications, including hydroxylation of proline and lysine residues and glycosylation, which are essential for the stability, proper folding, and assembly of the collagen triple helix structure. These modifications facilitate the formation of strong intermolecular cross-links, which are critical for the mechanical properties and resilience of connective tissues. Additionally, COL1A2 is involved in cell adhesion processes, contributing to the maintenance of normal tissue architecture and function. Anti-COL1A2 antibody (E-6) exhibits broad species reactivity, effectively detecting Collagen α2 Type I in mouse, rat, and human samples, as well as in additional species such as canine, bovine, and porcine, making COL1A2 (E-6) antibody an invaluable tool for comparative studies and research involving various animal models. Available in both non-conjugated and multiple conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and various Alexa Fluor® conjugates, COL1A2 (E-6) monoclonal antibody offers versatility for diverse experimental setups. By targeting the essential regions and post-translationally modified sites of COL1A2, anti-COL1A2 antibody (E-6) enables detailed investigations into the molecular mechanisms governing tissue integrity, repair, and pathological conditions such as fibrosis and connective tissue disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COL1A2 Antibody (E-6) | sc-393573 | 200 µg/ml | $316.00 | |||
COL1A2 Antibody (E-6): m-IgGλ BP-HRP Bundle | sc-524005 | 200 µg Ab, 40 µg BP | $354.00 | |||
COL1A2 Antibody (E-6) AC | sc-393573 AC | 500 µg/ml, 25% agarose | $416.00 | |||
COL1A2 Antibody (E-6) HRP | sc-393573 HRP | 200 µg/ml | $316.00 | |||
COL1A2 Antibody (E-6) FITC | sc-393573 FITC | 200 µg/ml | $330.00 | |||
COL1A2 Antibody (E-6) PE | sc-393573 PE | 200 µg/ml | $343.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 488 | sc-393573 AF488 | 200 µg/ml | $357.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 546 | sc-393573 AF546 | 200 µg/ml | $357.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 594 | sc-393573 AF594 | 200 µg/ml | $357.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 647 | sc-393573 AF647 | 200 µg/ml | $357.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 680 | sc-393573 AF680 | 200 µg/ml | $357.00 | |||
COL1A2 Antibody (E-6) Alexa Fluor® 790 | sc-393573 AF790 | 200 µg/ml | $357.00 | |||
COL1A2 (E-6) Neutralizing Peptide | sc-393573 P | 100 µg/0.5 ml | $68.00 |