COL14A1 Antibody (1C8): sc-517033
- COL14A1 Antibody (1C8) is a mouse monoclonal IgG2a κ COL14A1 antibody provided at 100 µg/ml
- raised against amino acids 1-759 representing full length COL14A1 of human origin
- recommended for detection of COL14A1 of human origin by WB, IP and ELISA
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for COL14A1 Antibody (1C8). This work is in progress.
COL14A1 Antibody (1C8) is a mouse monoclonal IgG2a kappa light chain antibody that detects COL14A1 protein of human origin by western blotting (WB), immunoprecipitation (IP), and enzyme-linked immunosorbent assay (ELISA). Anti-COL14A1 antibody (1C8) is available as a non-conjugated format. COL14A1, also known as collagen alpha-1(XIV) chain or undulin, is a 1,796 amino acid secreted protein that plays a crucial role in the structural integrity of the extracellular matrix. COL14A1 belongs to the fibril-associated collagens with interrupted helices (FACIT) family and exists in three alternatively spliced isoforms, which allows for functional diversity in tissue-specific contexts. COL14A1 is particularly important for the integration of collagen bundles, facilitating the formation of complex connective tissues. COL14A1′s localization to the extracellular matrix is vital for maintaining tissue architecture and function, as COL14A1 interacts with other collagen types and matrix components to provide tensile strength and support. This extensive family of collagen proteins, including COL14A1, is essential for the proper functioning of connective tissues such as tendons and cartilage, highlighting COL14A1 monoclonal antibody (1C8)′s significance in research and diagnostic applications related to connective tissue disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
COL14A1 Antibody (1C8) References:
- Collagen and bone strength. | Boskey, AL., et al. 1999. J Bone Miner Res. 14: 330-5. PMID: 10027897
- Review article: platelet-collagen interactions: membrane receptors and intracellular signalling pathways. | Alberio, L. and Dale, GL. 1999. Eur J Clin Invest. 29: 1066-76. PMID: 10583456
- Cell adhesion to collagenous matrices. | McCarthy, JB., et al. 1996. Biopolymers. 40: 371-81. PMID: 8765608
- Versatile collagens in invertebrates. | Engel, J. 1997. Science. 277: 1785-6. PMID: 9324767
- The cartilage collagens: a review of their structure, organization, and role in the pathogenesis of experimental arthritis in animals and in human rheumatic disease. | Cremer, MA., et al. 1998. J Mol Med (Berl). 76: 275-88. PMID: 9535561
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
COL14A1 Antibody (1C8) | sc-517033 | 100 µg/ml | $322.00 |