CNG-β3 Antibody (C-4): sc-398211

CNG-β3 Antibody (C-4) is a mouse monoclonal IgG2b kappa light chain antibody that detects CNG-β3 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CNG-β3 (C-4) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CNG-β3, also known as cyclic-nucleotide-gated cation channel beta 3, plays a crucial role in cyclic nucleotide-gated channels, which are essential for sensory transduction in visual and olfactory systems. These channels are heteromeric complexes composed of alpha and beta subunits, where beta subunits, including CNG-β3, do not form functional channels independently but modulate properties of channels formed by alpha subunits. CNG-β3 is specifically activated by cyclic guanosine monophosphate (cGMP), leading to rod photoreceptor depolarization, which is vital for converting light signals into electrical signals in the retina. Additionally, CNG-β3 is expressed in select retinal photoreceptor cells and testis, and mutations in CNG-β3 can result in achromatopsia, a genetic condition characterized by impaired color vision and other visual deficiencies. Anti-CNG-β3 antibody (C-4) serves as an invaluable tool for researchers studying sensory transduction mechanisms and pathophysiology of related visual disorders.

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LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CNG-β3 Antibody (C-4) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-CNG-β3 Antibody (C-4) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CNG-β3 Antibody (C-4) Specifications

Alternate Product Name: CNG-β3

Product Clone Name: C-4

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 78-97

Epitope Target: CNG-β3

Epitope Species: human

Product Reactivity/Detection: CNG-β3

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for CNG-β3 Antibody (C-4): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred CNG-β3 antibody is CNG-β3 Antibody (H-3): sc-390088.