CLEC-2L Antibody (D-5): sc-390424
- CLEC-2L Antibody (D-5) is a mouse monoclonal IgG2b κ CLEC-2L antibody provided at 200 µg/ml
- specific for an epitope mapping between amino acids 157-195 within an internal region of CLEC-2L of human origin
- CLEC-2L Antibody (D-5) is recommended for detection of CLEC-2L of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-CLEC-2L Antibody (D-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for CLEC-2L Antibody (D-5) for WB and IHC(P) applications. These reagents are now offered in bundles with CLEC-2L Antibody (D-5) (see ordering information below).
CLEC-2L Antibody (D-5) is a mouse monoclonal IgG2b kappa light chain antibody that detects CLEC-2L protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CLEC-2L (D-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CLEC-2L protein, a member of the C-type lectin domain family 2, plays a crucial role in immune responses and cell signaling due to binding specific carbohydrate structures on cell surfaces, essential for mediating interactions between immune cells and pathogens. This single-pass membrane protein, consisting of 214 amino acids, contains one C-type lectin domain and resides primarily on immune cell surfaces, where CLEC-2L participates in glycoprotein recognition and contributes to immune response regulation. CLEC-2L gene is located on human chromosome 7, a region associated with various genetic disorders, highlighting CLEC-2L′s importance in both health and disease. Understanding CLEC-2L function and interactions can provide insights into immune system regulation and potential therapeutic applications.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CLEC-2L Antibody (D-5) References:
- C-type lectin-like domains. | Drickamer, K. 1999. Curr Opin Struct Biol. 9: 585-90. PMID: 10508765
- Long-term audiological feature in Pendred syndrome caused by PDS mutation. | Iwasaki, S., et al. 2001. Arch Otolaryngol Head Neck Surg. 127: 705-8. PMID: 11405873
- Molecular and genomic characterization of human DLEC, a novel member of the C-type lectin receptor gene family preferentially expressed on monocyte-derived dendritic cells. | Arce, I., et al. 2001. Eur J Immunol. 31: 2733-40. PMID: 11536172
- Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily. | Ebner, S., et al. 2003. Proteins. 53: 44-55. PMID: 12945048
- The C-type lectin fold as an evolutionary solution for massive sequence variation. | McMahon, SA., et al. 2005. Nat Struct Mol Biol. 12: 886-92. PMID: 16170324
- C-type lectins on dendritic cells and their interaction with pathogen-derived and endogenous glycoconjugates. | Gijzen, K., et al. 2006. Curr Protein Pept Sci. 7: 283-94. PMID: 16918443
- [Williams-Beuren syndrome]. | Gilbert-Dussardier, B. 2006. Rev Prat. 56: 2102-6. PMID: 17416045
- Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta. | Tsipouras, P., et al. 1983. J Clin Invest. 72: 1262-7. PMID: 6313757
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CLEC-2L Antibody (D-5) | sc-390424 | 200 µg/ml | $322.00 | |||
CLEC-2L Antibody (D-5): m-IgG Fc BP-HRP Bundle | sc-526158 | 200 µg Ab; 10 µg BP | $361.00 | |||
CLEC-2L Antibody (D-5): m-IgG2b BP-HRP Bundle | sc-549688 | 200 µg Ab; 10 µg BP | $361.00 | |||
CLEC-2L Antibody (D-5) AC | sc-390424 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CLEC-2L Antibody (D-5) HRP | sc-390424 HRP | 200 µg/ml | $322.00 | |||
CLEC-2L Antibody (D-5) FITC | sc-390424 FITC | 200 µg/ml | $336.00 | |||
CLEC-2L Antibody (D-5) PE | sc-390424 PE | 200 µg/ml | $349.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 488 | sc-390424 AF488 | 200 µg/ml | $364.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 546 | sc-390424 AF546 | 200 µg/ml | $364.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 594 | sc-390424 AF594 | 200 µg/ml | $364.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 647 | sc-390424 AF647 | 200 µg/ml | $364.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 680 | sc-390424 AF680 | 200 µg/ml | $364.00 | |||
CLEC-2L Antibody (D-5) Alexa Fluor® 790 | sc-390424 AF790 | 200 µg/ml | $364.00 | |||
CLEC-2L (D-5) Neutralizing Peptide | sc-390424 P | 100 µg/0.5 ml | $69.00 |