CKR-10 Antibody (C-5): sc-365531
- CKR-10 Antibody (C-5) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- raised against amino acids 141-290 mapping within an internal region of CKR-10 of human origin
- recommended for detection of CKR-10 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CKR-10 Antibody (C-5) for WB applications. These reagents are now offered in bundles with CKR-10 Antibody (C-5) (see ordering information below).
CKR-10 Antibody (C-5) is a mouse monoclonal IgG2b antibody that detects CKR-10 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CKR-10, also known as CCR10 or GPR2, is a member of the C-C chemokine receptor family and serves as a specific receptor for the chemokines CCL27 and CCL28, which are crucial for the recruitment of immune cells to sites of inflammation. CKR-10 is predominantly expressed in the testis, small intestine, fetal lung, and fetal kidney, indicating a significant role in developmental processes and tissue homeostasis. Notably, CKR-10′s expression in adult tissues such as melanocytes and dermal fibroblasts suggests involvement in skin health and inflammatory responses, making CKR-10 an important target for studies related to immune regulation and dermatological conditions. Anti-CKR-10 antibody (C-5) provides a valuable tool for researchers investigating the mechanisms of chemotaxis and the role of chemokine receptors in various physiological and pathological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CKR-10 Antibody (C-5) References:
- Cutting edge: identification of the orphan receptor G-protein-coupled receptor 2 as CCR10, a specific receptor for the chemokine ESkine. | Jarmin, DI., et al. 2000. J Immunol. 164: 3460-4. PMID: 10725696
- Cutting edge: the orphan chemokine receptor G protein-coupled receptor-2 (GPR-2, CCR10) binds the skin-associated chemokine CCL27 (CTACK/ALP/ILC). | Homey, B., et al. 2000. J Immunol. 164: 3465-70. PMID: 10725697
- Identification of a novel chemokine (CCL28), which binds CCR10 (GPR2). | Wang, W., et al. 2000. J Biol Chem. 275: 22313-23. PMID: 10781587
- CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. | Homey, B., et al. 2002. Nat Med. 8: 157-65. PMID: 11821900
- Phosphodiesterase expression targeted to gonadotropin-releasing hormone neurons inhibits luteinizing hormone pulses in transgenic rats. | Paruthiyil, S., et al. 2002. Proc Natl Acad Sci U S A. 99: 17191-6. PMID: 12482943
- LET-99 opposes Galpha/GPR signaling to generate asymmetry for spindle positioning in response to PAR and MES-1/SRC-1 signaling. | Tsou, MF., et al. 2003. Development. 130: 5717-30. PMID: 14534135
- Evaluation of surgical gamma probes for sentinel node localization in cervical and vulvar cancer. | Wydra, D., et al. 2005. Nucl Med Rev Cent East Eur. 8: 105-10. PMID: 16437395
- Incorporating spike-rate adaptation into a rate code in mathematical and biological neurons. | Ralston, BN., et al. 2016. J Neurophysiol. 115: 2501-18. PMID: 26888106
- [Isolation and genetic analysis of bacterial mutations gpr blocking the replication of various lambda phages]. | Odoevskaia, ER. and Sineokiĭ, SP. 1987. Genetika. 23: 643-52. PMID: 2953652
- Contourlet-based hippocampal magnetic resonance imaging texture features for multivariant classification and prediction of Alzheimer's disease. | Gao, N., et al. 2018. Metab Brain Dis. 33: 1899-1909. PMID: 30178281
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CKR-10 Antibody (C-5) | sc-365531 | 200 µg/ml | $316.00 | |||
CKR-10 Antibody (C-5): m-IgGκ BP-HRP Bundle | sc-535216 | 200 µg Ab; 40 µg BP | $354.00 | |||
CKR-10 Antibody (C-5): m-IgG2b BP-HRP Bundle | sc-549368 | 200 µg Ab; 10 µg BP | $354.00 |