CIZ1 Antibody (2186C2a): sc-81069
- CIZ1 Antibody (2186C2a) is a mouse monoclonal IgG1 provided at 100 µg/ml
- raised against a recombinant protein corresponding to an internal region of CIZ1 of human origin
- recommended for detection of CIZ1 of human origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CIZ1 Antibody (2186C2a). This work is in progress.
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SEE ALSO...
CIZ1 Antibody (2186C2a) is a mouse monoclonal IgG1 antibody that detects CIZ1 in human samples through western blotting (WB) and immunoprecipitation (IP) applications. CIZ1, or Cip1-interacting zinc finger protein, is a crucial 898 amino acid nuclear protein encoded by the human gene CIZ1, belonging to the matrin 3 family and characterized by a single matrin-type zinc finger. This protein plays a significant role in DNA replication, as CIZ1 is involved in the regulation of cell cycle progression and the maintenance of genomic stability. The structure of CIZ1 is particularly important because CIZ1 consists of two distinct functional domains: an N-terminal replication domain that facilitates interaction with various cell cycle regulators, and a C-terminal nuclear matrix anchor that ensures proper localization within the nucleus. The spatial distribution of CIZ1 is influenced by alternative splicing, particularly the exclusion of exon 4, which can affect isoform expression and, consequently, functional role in DNA replication. Understanding the dynamics of CIZ1 and its interactions is vital for elucidating the mechanisms underlying cell proliferation and the potential implications in cancer biology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CIZ1 Antibody (2186C2a) | sc-81069 | 100 µg/ml | $333.00 |