ChoK Antibody (B-6): sc-390060
- ChoK Antibody (B-6) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 23-61 near the N-terminus of ChoK of human origin
- recommended for detection of ChoK of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ChoK Antibody (B-6) for WB applications. These reagents are now offered in bundles with ChoK Antibody (B-6) (see ordering information below).
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ChoK Antibody (B-6) is a mouse monoclonal IgG2b antibody that detects Choline Kinase in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Choline Kinase (B-6) antibody plays a crucial role in studying phosphatidylcholine biosynthesis, particularly through the CDP-choline pathway, where Choline Kinase serves as the initial enzyme. This enzyme is vital for cell growth and proliferation, and dysregulation has been linked to various human cancers, including breast, lung, colorectal, and prostate tumors. Notably, Choline Kinase is involved in producing phosphorylcholine, a metabolite often elevated in cancerous cells due to phospholipase D and Choline Kinase activation. The human Choline Kinase gene is located on chromosome 11q13.2, a region associated with several oncogenes, highlighting Choline Kinase′s importance in cancer biology. Anti-Choline Kinase antibody (B-6) enables researchers to gain insights into tumorigenesis mechanisms and potential therapeutic targets within the phosphatidylcholine biosynthetic pathway.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ChoK Antibody (B-6) | sc-390060 | 200 µg/ml | $322.00 | |||
ChoK Antibody (B-6): m-IgG Fc BP-HRP Bundle | sc-538058 | 200 µg Ab; 10 µg BP | $361.00 | |||
ChoK Antibody (B-6): m-IgGκ BP-HRP Bundle | sc-535585 | 200 µg Ab; 40 µg BP | $361.00 | |||
ChoK (B-6) Neutralizing Peptide | sc-390060 P | 100 µg/0.5 ml | $69.00 |