CD81 Antibody (B-11): sc-166029

CD81 Antibody (B-11) is a mouse monoclonal IgG2b kappa light chain antibody specifically designed to detect CD81, also known as TAPA-1. CD81 monoclonal antibody (B-11) is raised against amino acids 90-210 of human CD81 and is reactive with CD81 from mouse, rat, and human species, making it suitable for various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CD81 is a type III transmembrane protein characterized by four transmembrane domains, which facilitate integration into the cell membrane and enable participation in essential cellular processes. The structural configuration of CD81 allows formation of multimolecular complexes with other proteins such as CD37 and CD53, as well as interaction with CD19, CD21, and MHC class II antigens on B cells, thereby playing a crucial role in cell signaling and immune response regulation. This structural versatility is vital for functions in cell growth, differentiation, and communication, making CD81 a key player in maintaining cellular homeostasis and effective immune function. Widely expressed on cells of hematopoietic, neuroectodermal, and mesenchymal origin, CD81′s structural properties enable influence over diverse biological systems and processes. Anti-CD81 antibody (B-11) is available in both non-conjugated and various conjugated forms, including horseradish peroxidase (HRP) and fluorescent labels, providing researchers with flexibility for different experimental needs.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-CD81 Antibody (B-11) has 391 citations in a variety of scientific publications.

Primary antibodies like Anti-CD81 Antibody (B-11) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

CD81 Antibody (B-11) Specifications

Alternate Product Name: TAPA1

Product Clone Name: B-11

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 90-210

Epitope Target: CD81

Epitope Species: human

Product Reactivity/Detection: CD81

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 391 citations in various scientific publications

Available Conjugates/Forms for CD81 Antibody (B-11): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred CD81 antibody is CD81 Antibody (1.3.3.22): sc-7637.