CD74 Antibody (PIN.1): sc-47742
- CD74 Antibody (PIN.1) is a mouse monoclonal IgG1 κ, cited in 11 publications, provided at 200 µg/ml
- raised against a synthetic peptide DQKPVMDDQRDLISNNE, corresponding to amino acids 12-28 of human CD74
- recommended for detection of the epitope in a region of the cytoplasmic tail of CD74 of mouse, rat and human origin by WB, IP, IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD74 (LN-2): sc-6262 for CD74 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD74 Antibody (PIN.1) for WB and IHC(P) applications. These reagents are now offered in bundles with CD74 Antibody (PIN.1) (see ordering information below).
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SEE ALSO...
CD74 Antibody (PIN.1) is a mouse monoclonal IgG1 antibody that detects CD74 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating the loading of peptides onto major histocompatibility complex class II (MHC II) molecules. This process is vital for the proper presentation of antigens to T lymphocytes, which is essential for initiating adaptive immune responses. The interaction between CD74 and MHC II occurs during the transport of MHC II to the endosomal compartment, where peptide binding takes place. Notably, CD74 is expressed in a wide range of immune cells, particularly in B lymphocytes, and CD74 expression is critical for the development and function of these cells. Understanding CD74′s role in antigen presentation not only highlights CD74′s importance in immune responses but also underscores CD74′s potential as a therapeutic target in diseases where immune regulation is disrupted. Anti-CD74 antibody (PIN.1) is an invaluable tool for researchers studying immune function and related pathologies.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD74 Antibody (PIN.1) | sc-47742 | 200 µg/ml | $322.00 | |||
CD74 Antibody (PIN.1): m-IgG Fc BP-HRP Bundle | sc-536804 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD74 Antibody (PIN.1): m-IgGκ BP-HRP Bundle | sc-533969 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD74 Antibody (PIN.1) FITC | sc-47742 FITC | 200 µg/ml | $336.00 | |||
CD74 Antibody (PIN.1) PE | sc-47742 PE | 200 µg/ml | $349.00 |