Date published: 2026-5-3

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CD74 Antibody (OX6): sc-53062

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Datasheets
  • CD74 Antibody (OX6) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
  • raised against RT1b monomorphic/mouse -I-Ak,s of rat origin
  • recommended for detection of CD74 of mouse and rat origin by WB, IF, IHC(P) and FCM
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • See CD74 (LN-2): sc-6262 for CD74 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD74 Antibody (OX6) for WB and IHC(P) applications. These reagents are now offered in bundles with CD74 Antibody (OX6) (see ordering information below).
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CD74 Antibody (OX6) is a mouse monoclonal IgG1 antibody that detects CD74 in mouse and rat samples through various applications including western blotting (WB), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating the loading of peptides onto major histocompatibility complex class II (MHC II) molecules. This process is vital for the proper presentation of antigens to T lymphocytes, which is essential for initiating adaptive immune responses. CD74 is predominantly expressed in B lymphocytes and is also found in a subset of T lymphocytes, highlighting CD74′s importance in both humoral and cellular immunity. CD74 expression on immune cells not only facilitates the transport of MHC II to the endosomal compartment but also influences the stability and functionality of the MHC II-peptide complex. Understanding CD74′s role in immune responses can provide insights into various immunological disorders and potential therapeutic targets. Anti-CD74 antibody (OX6) serves as an invaluable tool for researchers studying immune cell interactions and the mechanisms of antigen presentation.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

CD74 Antibody (OX6)

sc-53062
200 µg/ml
$322.00

CD74 Antibody (OX6): m-IgG Fc BP-HRP Bundle

sc-536883
200 µg Ab; 10 µg BP
$361.00

CD74 Antibody (OX6): m-IgGκ BP-HRP Bundle

sc-534053
200 µg Ab; 40 µg BP
$361.00

CD74 Antibody (OX6): m-IgG1 BP-HRP Bundle

sc-544875
200 µg Ab; 20 µg BP
$361.00

CD74 Antibody (OX6) FITC

sc-53062 FITC
200 µg/ml
$336.00

CD74 Antibody (OX6) PE

sc-53062 PE
200 µg/ml
$349.00

I am working on rat dorsal root ganglion (DRG) samples and plan to perform Western blot and immunofluorescence on frozen sections. Could you please advise whether OX-6 or LN-2 is more suitable or has been validated for rat DRG in these applications?

Asked by: Kenzie
Thank you for your question. It would be helpful if you could email us directly at asia@scbio.cn. So we can have a more interactive discussion about this and other related issues.
Answered by: Zhanglong
Date published: 2026-01-30

Can CD74 (OX6): sc-53062 monoclonal antibody be used in IF or IHC with mouse tissue or cells? Will there be non-specific staining?

Asked by: Professor Griffin
Thank you for your inquiry. The use of mouse monoclonal antibodies with mouse samples is very common and typically poses no problem. To eliminate any potential cross-reactivity of an anti-mouse secondary detection reagent, CD74 (OX6): sc-53062 is available in a variety of direct conjugations, such as HRP, PE, FITC and AlexaFluors.
Answered by: Technical Support
Date published: 2017-02-24
  • y_2026, m_4, d_29, h_11CST
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Rated 5 out of 5 by from Great for Flow CytometryExcellent choice for CD74, gives nice Flow cytometry data!
Date published: 2017-02-03
Rated 5 out of 5 by from Publishable IHC data in rat spinal cord tissuePublishable IHC data in rat spinal cord tissue. -SCBT Publication Review
Date published: 2015-06-01
Rated 5 out of 5 by from Publishable data obtained by WB using mousePublishable data obtained by WB using mouse IKDC and NK from spleen. -SCBT Publication Review
Date published: 2015-05-19
Rated 5 out of 5 by from It has been reported that product scIt has been reported that product sc-53062 is suitable for use in IF using rat brain and dentate gyrus tissue. -SCBT Publication Review
Date published: 2015-01-27
Rated 4 out of 5 by from Produced robust indirect FCM data for ratProduced robust indirect FCM data for rat peripheral blood leukocytes stained CD74 . -SCBT QC
Date published: 2014-11-15
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CD74 Antibody (OX6) is rated 4.8 out of 5 by 5.
  • y_2026, m_4, d_29, h_11
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