CD74 Antibody (OX4): sc-53061
- CD74 Antibody (OX4) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against purified Ia glycoprotein of rat origin
- recommended for detection of CD74 of mouse and rat origin by IF, IHC(P) and FCM
- available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
- See CD74 (LN-2): sc-6262 for CD74 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD74 Antibody (OX4) for IHC(P) applications. These reagents are now offered in bundles with CD74 Antibody (OX4) (see ordering information below).
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SEE ALSO...
CD74 Antibody (OX4) is a mouse monoclonal IgG1 antibody that detects CD74 in mouse and rat samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating the loading of peptides onto major histocompatibility complex class II (MHC II) molecules. This process is vital for the proper presentation of antigens to T lymphocytes, which is essential for initiating adaptive immune responses. CD74 is predominantly expressed in B lymphocytes and is also found in a subset of T lymphocytes, highlighting CD74′s importance in both humoral and cellular immunity. CD74 expression on immune cells not only facilitates the transport of MHC II to the endosomal compartment but also influences the activation and differentiation of T cells, making CD74 a key player in immune regulation. With a broad expression profile and critical function in antigen presentation, CD74 serves as an important marker for studying immune responses and potential therapeutic targets in various diseases.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD74 Antibody (OX4) | sc-53061 | 200 µg/ml | $316.00 | |||
CD74 Antibody (OX4): m-IgG Fc BP-HRP Bundle | sc-536882 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD74 Antibody (OX4): m-IgGκ BP-HRP Bundle | sc-534052 | 200 µg Ab; 40 µg BP | $354.00 | |||
CD74 Antibody (OX4) FITC | sc-53061 FITC | 200 µg/ml | $330.00 | |||
CD74 Antibody (OX4) PE | sc-53061 PE | 200 µg/ml | $343.00 |