Date published: 2025-12-14

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CD74 Antibody (OX3): sc-53060

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Datasheets
  • CD74 Antibody (OX3) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
  • raised against 1a-RT1Bu of rat origin
  • recommended for detection of CD74 of mouse and rat origin by IF and FCM
  • available conjugated to either phycoerythrin or FITC for IF, IHC(P) and FCM
  • See CD74 (LN-2): sc-6262 for CD74 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
  • m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD74 Antibody (OX3). These reagents are now offered in bundles with CD74 Antibody (OX3) (see ordering information below).

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    CD74 Antibody (OX3) is a mouse monoclonal IgG1 antibody that detects CD74 in mouse and rat samples through applications such as immunofluorescence (IF) and flow cytometry (FCM). CD74, also known as the invariant chain, plays a crucial role in the immune system by regulating the loading of peptides onto major histocompatibility complex class II (MHC II) molecules. This process is vital for the proper presentation of antigens to T lymphocytes, which is essential for initiating adaptive immune responses. CD74 is predominantly expressed in B lymphocytes and is also found in a subset of T lymphocytes, highlighting CD74′s importance in both humoral and cellular immunity. CD74′s presence on these immune cells facilitates their interaction with MHC II, ensuring that the immune system can effectively recognize and respond to pathogens. Additionally, CD74 has been implicated in various cellular processes, including cell signaling and migration, making CD74 a significant target for research in immunology and potential therapeutic interventions. Anti-CD74 antibody (OX3) is an invaluable tool for studying these complex immune mechanisms and understanding CD74′s role in health and disease.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    CD74 Antibody (OX3)

    sc-53060
    200 µg/ml
    $316.00

    CD74 Antibody (OX3): m-IgG Fc BP-HRP Bundle

    sc-536881
    200 µg Ab; 10 µg BP
    $354.00

    CD74 Antibody (OX3): m-IgGκ BP-HRP Bundle

    sc-534051
    200 µg Ab; 40 µg BP
    $354.00

    CD74 Antibody (OX3): m-IgG1 BP-HRP Bundle

    sc-544874
    200 µg Ab; 20 µg BP
    $354.00

    CD74 Antibody (OX3) FITC

    sc-53060 FITC
    200 µg/ml
    $330.00

    CD74 Antibody (OX3) PE

    sc-53060 PE
    200 µg/ml
    $343.00

    How can CD74 (OX3): sc-53060 mouse monoclonal antibody be used for double or triple staining, if the other primary antibodies are also raised in mouse?

    Asked by: cjMara
    In this case, we recommend using a directly conjugated mouse monoclonal primary antibody. This antibody is available conjugated to phycoerythrin (sc-53060 PE) or fluoroscein (sc-53060 FITC).
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2025, m_12, d_7, h_8CST
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    Rated 3 out of 5 by from Produced satisfactory indirect FCM data forProduced satisfactory indirect FCM data for rat peripheral blood leukocytes stained CD74 . -SCBT QC
    Date published: 2014-05-04
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    CD74 Antibody (OX3) is rated 3.0 out of 5 by 1.
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