CD69 Antibody (FN50): sc-18880
- CD69 Antibody (FN50) is a mouse monoclonal IgG1 κ, cited in 3 publications, provided at 200 µg/ml
- raised against stimulated human B-lymphocytes
- recommended for detection of CD69 of human and primate origin by IF and FCM
- available conjugated to either phycoerythrin, FITC, Alexa Fluor® 488 or Alexa Fluor® 647 for IF, IHC(P) and FCM
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD69 Antibody (FN50). These reagents are now offered in bundles with CD69 Antibody (FN50) (see ordering information below).
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CD69 Antibody (FN50) is a mouse monoclonal IgG1 antibody that detects CD69 in human and primate samples through immunofluorescence (IF) and flow cytometry (FCM) applications. CD69 is a crucial activation marker expressed as a disulfide-linked homodimer known as the activation inducer molecule (AIM), which consists of two differentially glycosylated forms of a single protein. Anti-CD69 antibody (FN50) plays a vital role in studying immune responses, as CD69 is one of the earliest antigens to appear following the activation of T cells, B cells, and natural killer (NK) cells. CD69 presence on immune cells indicates readiness to respond to pathogens, making CD69 (FN50) monoclonal antibody an important marker for assessing immune activation and function. CD69 is constitutively expressed on platelets, CD4+ or CD8+ thymocytes, and germinal center T cells, while remaining absent from resting lymphocytes, highlighting CD69′s significance in distinguishing between activated and non-activated immune cells. Anti-CD69 antibody (FN50)′s ability to effectively identify CD69 in various applications makes this reagent an essential tool for researchers studying immune responses and related disorders.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CD69 Antibody (FN50) References:
- Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation. | Kimura, MY., et al. 2017. Immunol Rev. 278: 87-100. PMID: 28658550
- Using CD69 PET Imaging to Monitor Immunotherapy-Induced Immune Activation. | Edwards, KJ., et al. 2022. Cancer Immunol Res. 10: 1084-1094. PMID: 35862229
- CD69-oxLDL ligand engagement induces Programmed Cell Death 1 (PD-1) expression in human CD4 + T lymphocytes. | Jiménez-Fernández, M., et al. 2022. Cell Mol Life Sci. 79: 468. PMID: 35930205
- CD69 expression on regulatory T cells protects from immune damage after myocardial infarction. | Blanco-Domínguez, R., et al. 2022. J Clin Invest. 132: PMID: 36066993
- HSF1 promotes CD69+ Treg differentiation to inhibit colitis progression. | Yu, L., et al. 2023. Theranostics. 13: 1892-1905. PMID: 37064870
- CD69 Imposes Tumor-Specific CD8+ T-cell Fate in Tumor-Draining Lymph Nodes. | Koyama-Nasu, R., et al. 2023. Cancer Immunol Res. 11: 1085-1099. PMID: 37216576
- Unraveling CD69 signaling pathways, ligands and laterally associated molecules. | Jiménez-Fernández, M., et al. 2023. EXCLI J. 22: 334-351. PMID: 37223078
- The heterogeneity of tumour immune microenvironment revealing the CRABP2/CD69 signature discriminates distinct clinical outcomes in breast cancer. | Mei, J., et al. 2023. Br J Cancer. 129: 1645-1657. PMID: 37715025
- CD69 is a Promising Immunotherapy and Prognosis Prediction Target in Cancer. | Li, Y., et al. 2024. Immunotargets Ther. 13: 1-14. PMID: 38223406
- CD69 Signaling in Eosinophils Induces IL-10 Production and Apoptosis via the Erk1/2 and JNK Pathways, Respectively. | Bui, DV., et al. 2024. Biomolecules. 14: PMID: 38540778
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD69 Antibody (FN50) | sc-18880 | 200 µg/ml | $316.00 | |||
CD69 Antibody (FN50): m-IgG Fc BP-HRP Bundle | sc-536606 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD69 Antibody (FN50): m-IgGκ BP-HRP Bundle | sc-533761 | 200 µg Ab; 40 µg BP | $354.00 | |||
CD69 Antibody (FN50): m-IgG1 BP-HRP Bundle | sc-544702 | 200 µg Ab; 20 µg BP | $354.00 | |||
CD69 Antibody (FN50) Alexa Fluor® 488 | sc-18880 AF488 | 200 µg/ml | $357.00 | |||
CD69 Antibody (FN50) Alexa Fluor® 647 | sc-18880 AF647 | 200 µg/ml | $357.00 | |||
CD69 Antibody (FN50) FITC | sc-18880 FITC | 200 µg/ml | $330.00 | |||
CD69 Antibody (FN50) PE | sc-18880 PE | 200 µg/ml | $343.00 |