CD68 Antibody (SPM130): sc-52998
- CD68 Antibody (SPM130) is a mouse monoclonal IgG1 κ, cited in 8 publications, provided at 200 µg/ml
- raised against a subcellular fraction of human alveolar macrophages
- recommended for detection of CD68 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- See CD68 (KP1): sc-20060 for CD68 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for CD68 Antibody (SPM130) for WB and IHC(P) applications. These reagents are now offered in bundles with CD68 Antibody (SPM130) (see ordering information below).
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CD68 Antibody (SPM130) is a mouse monoclonal IgG1 antibody that detects CD68 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. CD68 is a member of a family of acidic, highly glycosylated lysosomal glycoproteins, which also includes lamp-1 and lamp-2, and plays a crucial role in the immune system. CD68 is primarily located in cytoplasmic granules and the cytoplasm of various non-hematopoietic tissues, such as liver and kidney tubules and glomeruli, as well as on the surface of immune cells like macrophages, monocytes, neutrophils, basophils, and large lymphocytes. CD68 presence on these immune cells serves as a marker for macrophage activation and is involved in the phagocytosis of pathogens and cellular debris, thereby contributing to the body′s defense mechanisms. Additionally, lysosomal glycoproteins like CD68 are essential components of lysosomal membranes, providing structural integrity and protection against degradation by hydrolases, which is vital for maintaining cellular homeostasis and function. Anti-CD68 antibody (SPM130) is an invaluable tool for researchers studying immune responses, cellular signaling, and lysosomal function in various biological contexts.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD68 Antibody (SPM130) | sc-52998 | 200 µg/ml | $316.00 | |||
CD68 Antibody (SPM130): m-IgG Fc BP-HRP Bundle | sc-536867 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD68 Antibody (SPM130): m-IgGκ BP-HRP Bundle | sc-534035 | 200 µg Ab; 40 µg BP | $354.00 | |||
CD68 Antibody (SPM130): m-IgG1 BP-HRP Bundle | sc-544867 | 200 µg Ab; 20 µg BP | $354.00 |