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CD37 Antibody (HD28) is a mouse monoclonal IgG2a antibody that detects CD37 in human samples through immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD37 is a crucial cell surface glycoprotein belonging to the tetra-spans transmembrane family, characterized by four hydrophobic, membrane-spanning domains. CD37 plays a significant role in mediating signal transduction events that influence cellular processes, including cell development, adhesion, activation, growth, and motility. CD37 is strongly expressed on normal and neoplastic mature sIg+ B cells, while showing lower levels on resting and activated T cells, neutrophils, granulocytes, and monocytes. CD37′s interaction with integrins and other tetra-spans transmembrane family proteins is vital for T-cell-B-cell interactions, which are essential for effective immune responses. Studies using transgenic mouse models lacking CD37 have shown no significant changes in the development and cellular composition of lymphoid organs, underscoring CD37′s importance in maintaining immune system integrity. Anti-CD37 antibody (HD28) is an invaluable tool for researchers studying immune cell interactions and CD37′s role in various pathological conditions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD37 Antibody (HD28) | sc-73364 | 200 µg/ml | $316.00 | |||
CD37 Antibody (HD28): m-IgG Fc BP-HRP Bundle | sc-539478 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD37 Antibody (HD28): m-IgG2a BP-HRP Bundle | sc-546714 | 200 µg Ab; 10 µg BP | $354.00 | |||
CD37 Antibody (HD28) FITC | sc-73364 FITC | 200 µg/ml | $330.00 | |||
CD37 Antibody (HD28) PE | sc-73364 PE | 200 µg/ml | $343.00 |