CD3-ε Antibody (145-2C11): sc-18871
- CD3-ε Antibody (145-2C11) is a Armenian hamster monoclonal IgG, cited in 6 publications, provided at 200 µg/ml
- raised against BM10-37 cytotoxic T lymphocyte of mouse origin
- CD3-epsilon Antibody (145-2C11) is recommended for detection of CD3-ε of mouse origin by WB, IP, IF, IHC(P) and FCM
- Anti-CD3-epsilon Antibody (145-2C11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to biotin for WB, IHC(P) and ELISA
- also provided azide-free for blocking, sc-18871 L, 200 µg/0.1 ml
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CD3-ε Antibody (145-2C11). This work is in progress.
QUICK LINKS
CD3-ε Antibody (145-2C11) is a hamster monoclonal IgG antibody that detects CD3-ε of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). CD3-ε (145-2C11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CD3-ε plays a crucial role in the immune response as a component of the T cell receptor (TCR) complex, which is essential for T cell activation and signaling. CD3-ε is located on the surface of T cells, where CD3-ε forms part of a multisubunit complex that transmits signals upon recognition of foreign antigens. CD3-ε initiates a cascade of intracellular signaling events that lead to T cell activation, proliferation, and differentiation, which are vital for an effective immune response. The CD3 complex, which includes CD3-ε, consists of five invariant polypeptide chains that form three distinct dimers, facilitating the transmission of signals that ultimately determine the fate of T cells in immune responses. Understanding the function and signaling mechanisms of CD3-ε is critical for developing therapeutic strategies targeting T cell-mediated diseases and enhancing immune responses in various clinical settings.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD3-ε Antibody (145-2C11) | sc-18871 | 200 µg/ml | $322.00 | |||
CD3-e Antibody (145-2C11) L | sc-18871 L | 200 µg/0.1 ml | $322.00 | |||
CD3-e Antibody (145-2C11) AC | sc-18871 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CD3-e Antibody (145-2C11) HRP | sc-18871 HRP | 200 µg/ml | $322.00 | |||
CD3-e Antibody (145-2C11) FITC | sc-18871 FITC | 200 µg/ml | $336.00 | |||
CD3-e Antibody (145-2C11) PE | sc-18871 PE | 200 µg/ml | $349.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 488 | sc-18871 AF488 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 546 | sc-18871 AF546 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 594 | sc-18871 AF594 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 647 | sc-18871 AF647 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 680 | sc-18871 AF680 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) Alexa Fluor® 790 | sc-18871 AF790 | 200 µg/ml | $364.00 | |||
CD3-e Antibody (145-2C11) B | sc-18871 B | 200 µg/ml | $326.00 |