CD1C Antibody (M241): sc-53192

CD1C Antibody (M241) is a mouse monoclonal IgG1 kappa light chain antibody that detects CD1C protein of human origin by immunoprecipitation (IP). CD1C is a member of the CD1 multigene family, which encodes five distinct forms of the CD1 T-cell surface glycoprotein in humans, namely CD1A, CD1B, CD1C, CD1D, and CD1E. anti-CD1C antibody (M241) plays a crucial role in studying immune system functions where CD1C presents lipid antigens to T lymphocytes, facilitating antigen recognition and subsequent immune response. CD1C is primarily located on the surface of various immune cells, including cortical thymocytes, Langerhans cells, and certain subsets of dendritic cells, which is significant for its function in antigen presentation and T cell activation. CD1C expression is tightly regulated and associates with β-2-Microglobulin, highlighting its importance in immune response. Additionally, CD1 protein trafficking is controlled by adaptor-protein complexes and CD1-associated chaperones, which are essential for the development and activation of CD1-restricted T cells. Understanding CD1C′s role in immune responses is vital, as CD1C can influence the effectiveness of T cell-mediated immunity and has implications in various immunological disorders. CD1C monoclonal antibody (M241) serves as an invaluable tool for researchers studying immune cell interactions and lipid antigen presentation mechanisms.

The preferred CD1C antibody is CD1C Antibody (B-6): sc-390980.