


CD19 Antibody (HD37) is a mouse monoclonal IgG1 antibody that detects CD19 in human samples through applications such as immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). CD19 is a crucial transmembrane glycoprotein that plays a significant role in B-cell development and activation. CD19 is selectively expressed on the surface of B-lymphocytes, where CD19 contains two extracellular immunoglobulin-like domains that facilitate the activation of intracellular signaling pathways, including the Ras and phosphatidylinositol 3-kinase pathways. The activation of CD19 leads to the cross-linking of membrane immunoglobulin chains and the recruitment of Src family protein tyrosine kinases, which are essential for B-cell signaling. Notably, CD19 is continuously expressed throughout B-cell development and remains present during the terminal differentiation of B-cells into plasma cells. Additionally, CD19 forms functional complexes with other B-lymphocyte surface proteins, such as integrin β1, CD21, and CD81, which are vital for regulating B-cell development and ensuring a robust immune response. Anti-CD19 antibody (HD37) is an invaluable tool for researchers studying B-cell biology and related immunological processes.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD19 Antibody (HD37) | sc-18894 | 200 µg/ml | $322.00 | |||
CD19 Antibody (HD37): m-IgG Fc BP-HRP Bundle | sc-536608 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD19 Antibody (HD37): m-IgGκ BP-HRP Bundle | sc-533763 | 200 µg Ab; 40 µg BP | $361.00 | |||
CD19 Antibody (HD37) FITC | sc-18894 FITC | 200 µg/ml | $336.00 | |||
CD19 Antibody (HD37) PE | sc-18894 PE | 200 µg/ml | $349.00 |