CD10 Antibody (2A1H5E1): sc-65990
- CD10 Antibody (2A1H5E1) is a mouse monoclonal IgG2b κ, cited in 1 publications, provided at 200 µg/ml
- raised against purified recombinant CD10 of human origin
- recommended for detection of CD10 of mouse, rat and human origin by WB, IP, IF and IHC(P)
- m-IgG Fc BP-HRP and m-IgG2b BP-HRP are the preferred secondary detection reagents for CD10 Antibody (2A1H5E1) for WB and IHC(P) applications. These reagents are now offered in bundles with CD10 Antibody (2A1H5E1) (see ordering information below).
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CD10 Antibody (2A1H5E1) is a mouse monoclonal IgG2b antibody that detects CD10 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. CD10, also known as the common acute lymphoblastic leukemia antigen (CALLA) and neutral endopeptidase (NEP), is a type II integral membrane glycoprotein that plays a crucial role in regulating peptide levels within the extracellular environment. As a zinc metalloprotease, CD10 cleaves various biologically active peptides, including Angiotensins I and II, which are vital for blood pressure regulation and fluid balance. CD10 expression is prominent in early B and T lymphoid precursors, B blasts, certain granulocytes, bone marrow stromal cells, and specific epithelial cells, including some tumor cell lines. CD10 presence serves as an important marker for diagnosing common acute lymphocytic leukemias and certain lymphomas, making anti-CD10 antibody (2A1H5E1) an essential tool for researchers and clinicians aiming to understand and investigate hematological malignancies and related disorders.
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CD10 Antibody (2A1H5E1) References:
- Expression of the CD10 antigen (neutral endopeptidase) by mesenchymal tumors of the skin. | Kanitakis, J., et al. 2000. Anticancer Res. 20: 3539-44. PMID: 11131659
- Immunohistochemical staining of CD10 in atypical fibroxanthomas. | Hultgren, TL. and DiMaio, DJ. 2007. J Cutan Pathol. 34: 415-9. PMID: 17448198
- CD10 expression in stromal cells of ameloblastoma variants. | Iezzi, G., et al. 2008. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 105: 206-9. PMID: 17942343
- BCL6, MUM1, and CD10 expression in mantle cell lymphoma. | Gualco, G., et al. 2010. Appl Immunohistochem Mol Morphol. 18: 103-8. PMID: 19826251
- CD 10 expression intensity in various grades and stages of urothelial carcinoma of urinary bladder. | Atique, M., et al. 2014. J Coll Physicians Surg Pak. 24: 351-5. PMID: 24848395
- Endoplasmic Reticulum Associated Degradation of Spinocerebellar Ataxia-Related CD10 Cysteine Mutant. | Kanuka, M., et al. 2020. Int J Mol Sci. 21: PMID: 32545905
- CD10 marks non-canonical PPARγ-independent adipocyte maturation and browning potential of adipose-derived stem cells. | Chakraborty, S., et al. 2021. Stem Cell Res Ther. 12: 109. PMID: 33541392
- A New CD10 Antibody Inhibits the Growth of Malignant Mesothelioma. | Mizutani, N., et al. 2021. Monoclon Antib Immunodiagn Immunother. 40: 21-27. PMID: 33625287
- IFITM1, CD10, SMA, and h-caldesmon as a helpful combination in differential diagnosis between endometrial stromal tumor and cellular leiomyoma. | Zhao, W., et al. 2021. BMC Cancer. 21: 1047. PMID: 34556086
- A Defucosylated Mouse Anti-CD10 Monoclonal Antibody (31-mG2a-f) Exerts Antitumor Activity in a Mouse Xenograft Model of CD10-Overexpressed Tumors. | Kawabata, H., et al. 2022. Monoclon Antib Immunodiagn Immunother. 41: 59-66. PMID: 35471051
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CD10 Antibody (2A1H5E1) | sc-65990 | 200 µg/ml | $322.00 | |||
CD10 Antibody (2A1H5E1): m-IgG Fc BP-HRP Bundle | sc-539201 | 200 µg Ab; 10 µg BP | $361.00 | |||
CD10 Antibody (2A1H5E1): m-IgG2b BP-HRP Bundle | sc-549736 | 200 µg Ab; 10 µg BP | $361.00 |