CCL14 Antibody (E-5): sc-28388

CCL14 Antibody (E-5) is a mouse monoclonal IgG2b antibody that detects CCL14 in human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). CCL14, a member of the intercrine β (chemokine C-C) family, plays a crucial role in the immune response by acting as a chemotactic factor that attracts immune cells such as monocytes, eosinophils, and T cells to sites of inflammation. This recruitment is vital for mounting an effective immune response, particularly in conditions where inflammation is a key component, such as in allergic reactions and chronic inflammatory diseases. The processed form of CCL14, known as HCC-1(9-74), exhibits enhanced receptor affinity and is recognized by CCR1, CCR3, and CCR5, which are important for mediating the chemotactic effects. Additionally, CCL14 activity is regulated by specific proteolytic processing, which is essential for function and interaction with target cells. Anti-CCL14 antibody (E-5) enables researchers to gain insights into the dynamics of immune cell migration and the underlying mechanisms of inflammatory responses, making CCL14 (E-5) antibody a valuable tool for studies in immunology and related fields.

The preferred CCL14 antibody is CCL14 Antibody (E-12): sc-376152.