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CASZ1 Antibody (B-11) is a mouse monoclonal IgG2b kappa light chain antibody that detects CASZ1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). CASZ1 Antibody (B-11) is available in non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CASZ1, also known as castor zinc finger 1, CST, SRG, or ZNF693, is a 1,759 amino acid transcription factor that plays a crucial role in regulating gene expression, particularly during development and cellular differentiation. Nuclear localization and eight C2H2-type zinc fingers are essential for DNA binding and interaction with other transcriptional regulators. CASZ1 is expressed in various tissues, including stomach, lung, testis, pancreas, heart, skeletal muscle, and small intestine, and exists as multiple alternatively spliced isoforms, contributing to diverse regulatory roles. Human CASZ1 shares over 85% sequence homology with mouse CASZ1, indicating conserved function across species. CASZ1 gene is located on human chromosome 1, a region associated with numerous disease-related genes, including those implicated in familial adenomatous polyposis, Stickler syndrome, Parkinson′s disease, Gaucher disease, schizophrenia, and Usher syndrome. Aberrations in chromosome 1 have been linked to various cancers, such as head and neck cancer, malignant melanoma, and multiple myeloma, underscoring CASZ1′s importance in normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CASZ1 Antibody (B-11) | sc-398303 | 200 µg/ml | $316.00 | |||
CASZ1 Antibody (B-11): m-IgG Fc BP-HRP Bundle | sc-530750 | 200 µg Ab; 10 µg BP | $354.00 | |||
CASZ1 Antibody (B-11): m-IgGκ BP-HRP Bundle | sc-524285 | 200 µg Ab, 40 µg BP | $354.00 | |||
CASZ1 Antibody (B-11): m-IgG2b BP-HRP Bundle | sc-550220 | 200 µg Ab; 10 µg BP | $354.00 | |||
CASZ1 Antibody (B-11) X | sc-398303 X | 200 µg/0.1 ml | $316.00 | |||
CASZ1 Antibody (B-11) AC | sc-398303 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CASZ1 Antibody (B-11) HRP | sc-398303 HRP | 200 µg/ml | $316.00 | |||
CASZ1 Antibody (B-11) FITC | sc-398303 FITC | 200 µg/ml | $330.00 | |||
CASZ1 Antibody (B-11) PE | sc-398303 PE | 200 µg/ml | $343.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 488 | sc-398303 AF488 | 200 µg/ml | $357.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 546 | sc-398303 AF546 | 200 µg/ml | $357.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 594 | sc-398303 AF594 | 200 µg/ml | $357.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 647 | sc-398303 AF647 | 200 µg/ml | $357.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 680 | sc-398303 AF680 | 200 µg/ml | $357.00 | |||
CASZ1 Antibody (B-11) Alexa Fluor® 790 | sc-398303 AF790 | 200 µg/ml | $357.00 | |||
CASZ1 (B-11) Neutralizing Peptide | sc-398303 P | 100 µg/0.5 ml | $68.00 |