CapG Antibody (B-9): sc-365473
- CapG Antibody (B-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 256-340 mapping at the C-terminus of CapG of human origin
- recommended for detection of CapG of human origin by WB, IP, IF and ELISA; non cross-reactive with mouse CapG
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for CapG Antibody (B-9) for WB applications. This reagent is now offered in a bundle with CapG Antibody (B-9) (see ordering information below).
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SEE ALSO...
CapG Antibody (B-9) is a mouse monoclonal IgG2a antibody that detects CapG in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CapG, also known as actin-regulatory protein or macrophage-capping protein, is a crucial actin-binding protein that plays a significant role in regulating actin filament dynamics. CapG is primarily expressed in macrophages and macrophage-like cells, where anti-CapG antibody (B-9) can detect its function in reversibly capping the barbed ends of actin filaments, preventing further polymerization while not severing existing filaments. This regulation is vital for maintaining cellular structure and facilitating processes such as cell migration and phagocytosis. Additionally, CapG is a calcium-sensitive DNA-binding protein, which allows participation in various cellular functions, including modulation of gene expression in response to calcium signaling. CapG′s ability to localize to both nucleus and cytoplasm underscores its importance in coordinating cellular responses and maintaining homeostasis in immune cells. CapG monoclonal antibody (B-9) serves as an essential tool for researchers studying actin dynamics and macrophage biology, providing insights into molecular mechanisms underlying immune responses and cellular architecture.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CapG Antibody (B-9) | sc-365473 | 200 µg/ml | $322.00 | |||
CapG Antibody (B-9): m-IgG Fc BP-HRP Bundle | sc-540343 | 200 µg Ab; 10 µg BP | $361.00 |