CaMKI Antibody (D-9): sc-377418
- CaMKI Antibody (D-9) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 343-370 at the C-terminus of CaMKI of human origin
- recommended for detection of CaMKI of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CaMKI Antibody (D-9) for WB applications. These reagents are now offered in bundles with CaMKI Antibody (D-9) (see ordering information below).
CaMKI Antibody (D-9) is a mouse monoclonal IgG1 antibody that detects CaMKI in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CaMKI, or calcium/calmodulin-dependent protein kinase I, plays a crucial role in various cellular processes, including the regulation of gene expression, cell growth, and differentiation, by acting as a key mediator in calcium signaling pathways. CaMKI is primarily located in the cytoplasm and nucleus, where CaMKI transduces calcium signals into cellular responses, making CaMKI essential for processes such as neuronal signaling and muscle contraction. CaMKI′s ability to translocate to the nucleus upon activation allows CaMKI to influence transcription factors and other nuclear proteins, thereby impacting gene expression and cellular function. Anti-CaMKI antibody (D-9) is an invaluable tool for researchers studying calcium signaling and its implications in various physiological and pathological conditions, including neurodegenerative diseases and cancer.
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CaMKI Antibody (D-9) References:
- Characterization of the role of CaMKI-like kinase (CKLiK) in human granulocyte function. | Verploegen, S., et al. 2005. Blood. 106: 1076-83. PMID: 15840691
- cAMP-induced expression of the orphan nuclear receptor Nur77 in MA-10 Leydig cells involves a CaMKI pathway. | Martin, LJ., et al. 2009. J Androl. 30: 134-45. PMID: 18835829
- CaMKK-CaMKI signaling pathways differentially control axon and dendrite elongation in cortical neurons. | Neal, AP., et al. 2010. J Neurosci. 30: 2807-9. PMID: 20181577
- Ca2+/calmodulin-dependent kinase (CaMK) signaling via CaMKI and AMP-activated protein kinase contributes to the regulation of WIPI-1 at the onset of autophagy. | Pfisterer, SG., et al. 2011. Mol Pharmacol. 80: 1066-75. PMID: 21896713
- Phosphorylation and activation of nuclear Ca2+/calmodulin-dependent protein kinase phosphatase (CaMKP-N/PPM1E) by Ca2+/calmodulin-dependent protein kinase I (CaMKI). | Onouchi, T., et al. 2012. Biochem Biophys Res Commun. 422: 703-9. PMID: 22627141
- Crystal structures of human CaMKIα reveal insights into the regulation mechanism of CaMKI. | Zha, M., et al. 2012. PLoS One. 7: e44828. PMID: 23028635
- Involvement of Epac1/Rap1/CaMKI/HDAC5 signaling cascade in the regulation of placental cell fusion. | Chang, CW., et al. 2013. Mol Hum Reprod. 19: 745-55. PMID: 23867755
- CaMKI-dependent regulation of sensory gene expression mediates experience-dependent plasticity in the operating range of a thermosensory neuron. | Yu, YV., et al. 2014. Neuron. 84: 919-926. PMID: 25467978
- The Phosphatase-Resistant Isoform of CaMKI, Ca²⁺/Calmodulin-Dependent Protein Kinase Iδ (CaMKIδ), Remains in Its 'Primed' Form without Ca²⁺ Stimulation. | Senga, Y., et al. 2015. Biochemistry. 54: 3617-30. PMID: 25994484
- 1800 MHz radiofrequency fields inhibits testosterone production via CaMKI /RORα pathway. | Qin, F., et al. 2018. Reprod Toxicol. 81: 229-236. PMID: 30125682
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CaMKI Antibody (D-9) | sc-377418 | 200 µg/ml | $316.00 | |||
CaMKI Antibody (D-9): m-IgG Fc BP-HRP Bundle | sc-551175 | 200 µg Ab; 10 µg BP | $354.00 | |||
CaMKI Antibody (D-9): m-IgG1 BP-HRP Bundle | sc-551176 | 200 µg Ab; 20 µg BP | $354.00 | |||
CaMKI (D-9) Neutralizing Peptide | sc-377418 P | 100 µg/0.5 ml | $68.00 |