Calgranulin B Antibody (MRP 1H9): sc-53187
- Calgranulin B Antibody (MRP 1H9) is a mouse monoclonal IgG1 κ, cited in 6 publications, provided at 200 µg/ml
- raised against recombinant MRP-14 of human origin
- Calgranulin B Antibody (MRP 1H9) is recommended for detection of Calgranulin B of human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-Calgranulin B Antibody (MRP 1H9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for Calgranulin B Antibody (MRP 1H9) for WB and IHC(P) applications. These reagents are now offered in bundles with Calgranulin B Antibody (MRP 1H9) (see ordering information below).
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Calgranulin B Antibody (MRP 1H9) is a mouse monoclonal IgG1 kappa light chain antibody that detects human Calgranulin B through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). Anti-Calgranulin B antibody (MRP 1H9) is available in non-conjugated form and conjugated to agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® dyes. Calgranulin B, also known as MRP14, belongs to the S100 protein family, characterized by EF-hand calcium-binding motifs. Calgranulin B plays a crucial role in inflammatory responses and regulates cellular processes, including cell proliferation and differentiation. Calgranulin B expression occurs in macrophages and epithelial cells, contributing to immune responses and acting as a signaling molecule. Calcium ion binding influences Calgranulin B′s conformation and interaction with other cellular components. Calgranulin B presence at inflammatory sites highlights its role in immune responses and potential as a biomarker for autoimmune disorders and cancer.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Calgranulin B Antibody (MRP 1H9) References:
- Isolation of a rat S100 alpha cDNA and distribution of its mRNA in rat tissues. | Zimmer, DB., et al. 1991. Brain Res Bull. 27: 157-62. PMID: 1742602
- Monoclonal antibodies to cystic fibrosis antigen. | Hayward, C., et al. 1986. J Immunol Methods. 91: 117-22. PMID: 2425000
- Tissue localization and chromosomal assignment of a serum protein that tracks the cystic fibrosis gene. | van Heyningen, V., et al. Nature. 315: 513-5. PMID: 2582274
- Antitumor effects of calgranulin B internalized in human colon cancer cells. | Kim, K., et al. 2016. Oncotarget. 7: 20368-80. PMID: 26933915
- Proteins that interact with calgranulin B in the human colon cancer cell line HCT-116. | Myung, JK., et al. 2017. Oncotarget. 8: 6819-6832. PMID: 28036279
- Identification of calgranulin B interacting proteins and network analysis in gastrointestinal cancer cells. | Kim, KH., et al. 2017. PLoS One. 12: e0171232. PMID: 28152021
- Expression pattern of two related cystic fibrosis-associated calcium-binding proteins in normal and abnormal tissues. | Wilkinson, MM., et al. 1988. J Cell Sci. 91 (Pt 2): 221-30. PMID: 3267695
- Developmental and functional studies of parvalbumin and calbindin D28K in hypothalamic neurons grown in serum-free medium. | Pfyffer, GE., et al. 1987. J Neurochem. 49: 442-51. PMID: 3298546
- Developmental appearance of the Ca2+-binding proteins parvalbumin, calbindin D-28K, S-100 proteins and calmodulin during testicular development in the rat. | Kägi, U., et al. 1988. Cell Tissue Res. 252: 359-65. PMID: 3383215
- Increase of skeletal muscle relaxation speed by direct injection of parvalbumin cDNA. | Müntener, M., et al. 1995. Proc Natl Acad Sci U S A. 92: 6504-8. PMID: 7604022
- Retinoic acid regulates the expression of the calcium binding protein, calbindin-D28K. | Wang, YZ. and Christakos, S. 1995. Mol Endocrinol. 9: 1510-21. PMID: 8584029
- A novel calcium-binding protein in amniotic fluid, CAAF1: its molecular cloning and tissue distribution. | Hitomi, J., et al. 1996. J Cell Sci. 109 (Pt 4): 805-15. PMID: 8718672
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Calgranulin B Antibody (MRP 1H9) | sc-53187 | 200 µg/ml | $322.00 | |||
Calgranulin B Antibody (MRP 1H9): m-IgG Fc BP-HRP Bundle | sc-526777 | 200 µg Ab; 10 µg BP | $361.00 | |||
Calgranulin B Antibody (MRP 1H9): m-IgG1 BP-HRP Bundle | sc-532150 | 200 µg Ab; 20 µg BP | $361.00 | |||
Calgranulin B Antibody (MRP 1H9) AC | sc-53187 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Calgranulin B Antibody (MRP 1H9) HRP | sc-53187 HRP | 200 µg/ml | $322.00 | |||
Calgranulin B Antibody (MRP 1H9) FITC | sc-53187 FITC | 200 µg/ml | $336.00 | |||
Calgranulin B Antibody (MRP 1H9) PE | sc-53187 PE | 200 µg/ml | $349.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 488 | sc-53187 AF488 | 200 µg/ml | $364.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 546 | sc-53187 AF546 | 200 µg/ml | $364.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 594 | sc-53187 AF594 | 200 µg/ml | $364.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 647 | sc-53187 AF647 | 200 µg/ml | $364.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 680 | sc-53187 AF680 | 200 µg/ml | $364.00 | |||
Calgranulin B Antibody (MRP 1H9) Alexa Fluor® 790 | sc-53187 AF790 | 200 µg/ml | $364.00 |