C1QBP Antibody (B-6): sc-271201

C1QBP Antibody (B-6) is a mouse monoclonal IgG1 antibody that detects C1QBP in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). C1QBP, also known as gC1q-R, p32, or hyaluronan-binding protein 1, plays a crucial role in the immune response by binding to the globular heads of C1q molecules, thereby inhibiting C1 activation and modulating the complement system. C1QBP is primarily located in vascular endothelial cells, where C1QBP is involved in multiple physiological processes, including the regulation of inflammation and immune responses. C1QBP presence in these cells is significant as C1QBP allows for the integration of signals from the complement, coagulation, and kinin systems, which are essential for maintaining homeostasis and responding to injury or infection. Additionally, C1QBP is a subunit of the pre-mRNA splicing factor SF2/ASF, highlighting C1QBP involvement in gene expression regulation. C1QBP ability to form homodimers further emphasizes its multifunctional nature, making C1QBP a vital component in various cellular processes.

The preferred C1QBP antibody is C1QBP Antibody (74.5.2): sc-23885.