c-Jun Antibody (B-1): sc-166540

c-Jun Antibody (B-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects c-Jun in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). anti-c-Jun antibody (B-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. c-Jun (B-1) antibody recognizes a key component of the transcription factor AP-1, which regulates gene expression in response to growth factors and stress signals. c-Jun′s ability to form homo- and heterodimers with other Jun and Fos oncogene family members enables binding to the TPA-response element (TRE) with high affinity, influencing genes involved in cell proliferation and survival. c-Jun (B-1) monoclonal antibody targets a protein whose interaction with Ha-Ras enhances transcriptional activity, highlighting c-Jun′s importance in oncogenic signaling pathways. Post-translational modifications, such as phosphorylation through the cAMP-dependent protein kinase A pathway, modulate c-Jun activity, emphasizing c-Jun′s significance in cellular responses and potential as a therapeutic target in cancer research.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-c-Jun Antibody (B-1) has 39 citations in a variety of scientific publications.

Primary antibodies like Anti-c-Jun Antibody (B-1) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

c-Jun Antibody (B-1) Specifications

Alternate Product Name: c-Jun

Product Clone Name: B-1

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 91-105

Epitope Target: c-Jun

Epitope Species: mouse

Product Reactivity/Detection: c-Jun

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: canine, bovine, porcine and avian

Additional Non-Mammalian Reactivity: avian

Applications: WB, IP, IF, IHC(P), ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 39 citations in various scientific publications

Available Conjugates/Forms for c-Jun Antibody (B-1): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin, X: TransCruz Reagent

The preferred p-c-Jun antibody is p-c-Jun Antibody (KM-1): sc-822.