BTEB1 Antibody (E-8): sc-376423

BTEB1 Antibody (E-8) is a mouse monoclonal IgG2b antibody that detects BTEB1 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BTEB1, a member of the C2H2 zinc finger family, plays a crucial role in regulating gene expression by binding to GC-rich motifs found in gene promoters, which can lead to either activation or repression of transcriptional activities. BTEB1 is predominantly localized in the nuclei of endometrial luminal and glandular epithelial cells, highlighting its importance in cellular regulation and signaling. Notably, BTEB1 expression is inducible by environmental factors such as acetaldehyde and ultraviolet light, which suggests involvement in cellular responses to stress and injury. Furthermore, BTEB1 is essential for pregnancy-associated endometrial epithelial gene expression and has been shown to mediate JNK-dependent alpha (I) collagen gene expression in hepatic stellate cells, underscoring significance in both reproductive biology and liver function. Anti-BTEB1 antibody (E-8) is an invaluable tool for researchers studying gene regulation and cellular responses in various physiological and pathological contexts.

The preferred BTEB1 antibody is BTEB1 Antibody (A-5): sc-376422.