BTEB1 Antibody (A-5): sc-376422
- BTEB1 Antibody (A-5) is a mouse monoclonal IgG2a κ BTEB1 antibody, cited in 12 publications, provided at 200 µg/ml
- raised against amino acids 21-150 of BTEB1 of human origin
- BTEB1 Antibody (A-5) is recommended for detection of BTEB1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-BTEB1 Antibody (A-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BTEB1 Antibody (A-5) for WB applications. These reagents are now offered in bundles with BTEB1 Antibody (A-5) (see ordering information below).
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BTEB1 Antibody (A-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects BTEB1 of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BTEB1 (A-5) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BTEB1, a member of the C2H2 zinc finger family, plays a crucial role in gene regulation by binding to GC-rich motifs found in gene promoters, which can lead to either activation or repression of transcriptional activities. BTEB1 is predominantly localized in the nuclei of endometrial luminal and glandular epithelial cells, where BTEB1 is induced by acetaldehyde and ultraviolet light, highlighting BTEB1′s importance in cellular responses to environmental stimuli. BTEB1 is particularly significant in regulating pregnancy-associated gene expression in the endometrium and mediating JNK-dependent alpha (I) collagen gene expression in hepatic stellate cells, making BTEB1 a vital player in both reproductive biology and liver fibrosis.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BTEB1 Antibody (A-5) References:
- Trans-activation functions of the Sp-related nuclear factor, basic transcription element-binding protein, and progesterone receptor in endometrial epithelial cells. | Simmen, RC., et al. 1999. Endocrinology. 140: 2517-25. PMID: 10342837
- The DNA binding protein BTEB mediates acetaldehyde-induced, jun N-terminal kinase-dependent alphaI(I) collagen gene expression in rat hepatic stellate cells. | Chen, A. and Davis, BH. 2000. Mol Cell Biol. 20: 2818-26. PMID: 10733585
- Purification and characterization of the DNA-binding domain of BTEB, a GC box-binding transcription factor, expressed in Escherichia coli. | Kikuchi, Y., et al. 1996. J Biochem. 119: 309-13. PMID: 8882723
- Cell-type expression, immunolocalization, and deoxyribonucleic acid-binding activity of basic transcription element binding transcription factor, an Sp-related family member, in porcine endometrium of pregnancy. | Wang, Y., et al. 1997. Biol Reprod. 57: 707-14. PMID: 9314570
- Transcriptional regulation by the Sp family proteins. | Lania, L., et al. 1997. Int J Biochem Cell Biol. 29: 1313-23. PMID: 9570130
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BTEB1 Antibody (A-5) | sc-376422 | 200 µg/ml | $322.00 | |||
BTEB1 Antibody (A-5): m-IgGκ BP-HRP Bundle | sc-522952 | 200 µg Ab, 40 µg BP | $361.00 | |||
BTEB1 Antibody (A-5): m-IgG2a BP-HRP Bundle | sc-546127 | 200 µg Ab; 10 µg BP | $361.00 | |||
BTEB1 Antibody (A-5) AC | sc-376422 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BTEB1 Antibody (A-5) HRP | sc-376422 HRP | 200 µg/ml | $322.00 | |||
BTEB1 Antibody (A-5) FITC | sc-376422 FITC | 200 µg/ml | $336.00 | |||
BTEB1 Antibody (A-5) PE | sc-376422 PE | 200 µg/ml | $349.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 488 | sc-376422 AF488 | 200 µg/ml | $364.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 546 | sc-376422 AF546 | 200 µg/ml | $364.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 594 | sc-376422 AF594 | 200 µg/ml | $364.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 647 | sc-376422 AF647 | 200 µg/ml | $364.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 680 | sc-376422 AF680 | 200 µg/ml | $364.00 | |||
BTEB1 Antibody (A-5) Alexa Fluor® 790 | sc-376422 AF790 | 200 µg/ml | $364.00 |