BRCA1 Antibody (287.17): sc-135732
- BRCA1 Antibody (287.17) is a mouse monoclonal IgG2b κ, cited in 11 publications, provided at 200 µg/ml
- raised against recombinant BRCA1 of mouse origin
- recommended for detection of BRCA1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- See BRCA1 (247.56): sc-135731 for BRCA1 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG2b BP-HRP is the preferred secondary detection reagent for BRCA1 Antibody (287.17) for WB and IHC(P) applications. This reagent is now offered in a bundle with BRCA1 Antibody (287.17) (see ordering information below).
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BRCA1 Antibody (287.17) is a mouse monoclonal IgG2b antibody that detects BRCA1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). BRCA1 plays a crucial role in maintaining genomic stability and is essential for the repair of DNA double-strand breaks through homologous recombination, a process vital for preventing mutations that can lead to cancer. BRCA1 is predominantly located in the nucleus, where BRCA1 interacts with other proteins involved in DNA repair and cell cycle regulation, underscoring BRCA1′s importance in tumor suppression. Mutations in the BRCA1 gene can disrupt these critical functions, leading to an increased risk of breast and ovarian cancers, making BRCA1 research essential for understanding cancer biology and developing targeted therapies. Anti-BRCA1 antibody (287.17) is an invaluable tool for researchers investigating the molecular mechanisms of cancer and BRCA1′s role in tumorigenesis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BRCA1 Antibody (287.17) | sc-135732 | 200 µg/ml | $316.00 | |||
BRCA1 Antibody (287.17): m-IgG2b BP-HRP Bundle | sc-548493 | 200 µg Ab; 10 µg BP | $354.00 |