Date published: 2025-9-5

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BRCA2 Antibodies

Santa Cruz Biotechnology provides a broad selection of BRCA2 monoclonal antibodies for investigating BRCA2 protein's role in cellular processes. BRCA2 monoclonal antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). BRCA2 is a critical protein involved in the repair of DNA double-strand breaks, playing a vital role in maintaining genomic stability. Mutations in the BRCA2 gene are associated with an increased risk of breast and ovarian cancers, making it a significant focus of cancer research. Understanding the function and regulation of BRCA2 is essential for developing targeted therapies and improving patient outcomes. BRCA2 monoclonal antibodies enable detailed analysis of protein expression patterns across different cell types and tissues. Researchers can examine BRCA2 localization within cellular compartments and study its interactions with other proteins involved in DNA repair pathways. Advanced research with BRCA2 monoclonal antibodies from Santa Cruz Biotechnology continues to drive discoveries in cancer biology and therapeutic development.

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BRCA2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

BRCA2 Antibody (D-8)

sc-518154mouse IgG1 κ1-300 (h)WB, IP, IF, ELISAh
2
(2)

BRCA2 Antibody (3D12)

sc-293185mouse IgG3 κ3319-3418 (h)WB, IP, ELISAh
10
(5)

BRCA2 Antibody (1643CT739.91.87)

sc-517316mouse IgG1 κ251-495 (h)WBh

new

(0)

BRCA2 Antibody (184H2N)

sc-517636mouse IgG1 κ(h)WBh

new

(0)

BRCA2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRCA2 CRISPR/Cas9 KO Plasmid (h)

sc-400700hGene KnockoutGFP
4
(0)

BRCA2 HDR Plasmid (h)

sc-400700-HDRhHomology Directed RepairPuromycin
4
(0)

BRCA2 Double Nickase Plasmid (h)

sc-400700-NIChGene KnockoutPuromycin
4
(0)

BRCA2 Double Nickase Plasmid (h2)

sc-400700-NIC-2hGene KnockoutPuromycin
4
(0)

BRCA2 CRISPR/Cas9 KO Plasmid (m)

sc-419363mGene KnockoutGFP0
(0)

BRCA2 HDR Plasmid (m)

sc-419363-HDRmHomology Directed RepairPuromycin0
(0)

BRCA2 Double Nickase Plasmid (m)

sc-419363-NICmGene KnockoutPuromycin0
(0)

BRCA2 Double Nickase Plasmid (m2)

sc-419363-NIC-2mGene KnockoutPuromycin0
(0)

BRCA2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRCA2 CRISPR Activation Plasmid (h)

sc-400700-ACThGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 CRISPR Activation Plasmid (h2)

sc-400700-ACT-2hGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 Lentiviral Activation Particles (h)

sc-400700-LAChGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 Lentiviral Activation Particles (h2)

sc-400700-LAC-2hGene ActivationPuro, Blast, Hygro
4
(0)

BRCA2 CRISPR Activation Plasmid (m)

sc-419363-ACTmGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 CRISPR Activation Plasmid (m2)

sc-419363-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 Lentiviral Activation Particles (m)

sc-419363-LACmGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 Lentiviral Activation Particles (m2)

sc-419363-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

BRCA2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

BRCA2 siRNA (h)

sc-29825hGene SilencingN/A
14
(0)

BRCA2 shRNA Plasmid (h)

sc-29825-SHhGene SilencingPuromycin
14
(0)

BRCA2 shRNA (h) Lentiviral Particles

sc-29825-VhGene SilencingPuromycin
14
(0)

BRCA2 siRNA (m)

sc-29826mGene SilencingN/A0
(0)

BRCA2 shRNA Plasmid (m)

sc-29826-SHmGene SilencingPuromycin0
(0)

BRCA2 shRNA (m) Lentiviral Particles

sc-29826-VmGene SilencingPuromycin0
(0)