BCDIN3D Antibody (F-5): sc-390348
- BCDIN3D Antibody (F-5) is a mouse monoclonal IgG2a κ BCDIN3D antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 32-48 near the N-terminus of BCDIN3D of human origin
- BCDIN3D Antibody (F-5) is recommended for detection of BCDIN3D of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
- Anti-BCDIN3D Antibody (F-5) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BCDIN3D Antibody (F-5) for WB and IHC(P) applications. These reagents are now offered in bundles with BCDIN3D Antibody (F-5) (see ordering information below).
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BCDIN3D Antibody (F-5) is a mouse monoclonal IgG2a kappa light chain antibody that detects BCDIN3D protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Anti-BCDIN3D antibody (F-5) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BCDIN3D protein, consisting of 292 amino acids, is a member of the methyltransferase superfamily and contains a single BIN3 domain. BCDIN3D (F-5) antibody recognizes a protein that plays a significant role in cellular processes related to methylation, which is crucial for regulating gene expression and protein function. Dysregulation of methyltransferases like BCDIN3D has been associated with metabolic disorders, including obesity and variations in body mass index. BCDIN3D (F-5) monoclonal antibody targets a protein encoded by a gene located on human chromosome 12, a region linked to various skeletal deformities and developmental syndromes, highlighting BCDIN3D′s importance in both health and disease. Understanding BCDIN3D function and its implications in metabolic regulation can provide valuable insights into potential therapeutic targets for obesity and related conditions.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BCDIN3D Antibody (F-5) References:
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg, RL., et al. 2002. Proc Natl Acad Sci U S A. 99: 16899-903. PMID: 12477932
- The genetic contribution to non-syndromic human obesity. | Walley, AJ., et al. 2009. Nat Rev Genet. 10: 431-42. PMID: 19506576
- Implication of genetic variants near NEGR1, SEC16B, TMEM18, ETV5/DGKG, GNPDA2, LIN7C/BDNF, MTCH2, BCDIN3D/FAIM2, SH2B1, FTO, MC4R, and KCTD15 with obesity and type 2 diabetes in 7705 Chinese. | Ng, MC., et al. 2010. J Clin Endocrinol Metab. 95: 2418-25. PMID: 20215397
- Pericentric inversion (12)(p12q13-14) as the sole chromosomal abnormality in a leiomyoma of the vulva. | Guardiola, MT., et al. 2010. Cancer Genet Cytogenet. 199: 21-3. PMID: 20417864
- Two new Loci for body-weight regulation identified in a joint analysis of genome-wide association studies for early-onset extreme obesity in French and german study groups. | Scherag, A., et al. 2010. PLoS Genet. 6: e1000916. PMID: 20421936
- Deletion mapping of chromosome region 12q13-24 in colorectal cancer. | Aytekin, T., et al. 2010. Cancer Genet Cytogenet. 201: 32-8. PMID: 20633766
- Noonan syndrome: A case report. | Ierardo, G., et al. 2010. Eur J Paediatr Dent. 11: 97-100. PMID: 20635845
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BCDIN3D Antibody (F-5) | sc-390348 | 200 µg/ml | $322.00 | |||
BCDIN3D Antibody (F-5): m-IgG Fc BP-HRP Bundle | sc-530132 | 200 µg Ab; 10 µg BP | $361.00 | |||
BCDIN3D Antibody (F-5): m-IgGκ BP-HRP Bundle | sc-523502 | 200 µg Ab, 40 µg BP | $361.00 | |||
BCDIN3D Antibody (F-5): m-IgG2a BP-HRP Bundle | sc-547442 | 200 µg Ab; 10 µg BP | $361.00 | |||
BCDIN3D Antibody (F-5) AC | sc-390348 AC | 500 µg/ml, 25% agarose | $424.00 | |||
BCDIN3D Antibody (F-5) HRP | sc-390348 HRP | 200 µg/ml | $322.00 | |||
BCDIN3D Antibody (F-5) FITC | sc-390348 FITC | 200 µg/ml | $336.00 | |||
BCDIN3D Antibody (F-5) PE | sc-390348 PE | 200 µg/ml | $349.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 488 | sc-390348 AF488 | 200 µg/ml | $364.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 546 | sc-390348 AF546 | 200 µg/ml | $364.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 594 | sc-390348 AF594 | 200 µg/ml | $364.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 647 | sc-390348 AF647 | 200 µg/ml | $364.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 680 | sc-390348 AF680 | 200 µg/ml | $364.00 | |||
BCDIN3D Antibody (F-5) Alexa Fluor® 790 | sc-390348 AF790 | 200 µg/ml | $364.00 | |||
BCDIN3D (F-5) Neutralizing Peptide | sc-390348 P | 100 µg/0.5 ml | $69.00 |