BCAM Antibody (D-6): sc-365191
- BCAM Antibody (D-6) is a mouse monoclonal IgG2b κ, cited in 3 publications, provided at 200 µg/ml
- raised against amino acids 258-301 mapping within an internal region of BCAM of human origin
- BCAM Antibody (D-6) is recommended for detection of BCAM of human origin by WB, IP, IF and ELISA
- Anti-BCAM Antibody (D-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for BCAM Antibody (D-6) for WB applications. These reagents are now offered in bundles with BCAM Antibody (D-6) (see ordering information below).
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SEE ALSO...
BCAM Antibody (D-6) is a mouse monoclonal IgG2b kappa light chain antibody that detects human BCAM through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). BCAM (D-6) antibody is available in non-conjugated form and various conjugates, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. BCAM, also known as Lutheran blood group glycoprotein, functions as a cell adhesion molecule mediating cell-cell and cell-matrix interactions. BCAM plays essential roles in embryonic development, immune response, and synaptic adhesion regulation in neurons, contributing to learning and memory processes. BCAM (D-6) monoclonal antibody recognizes BCAM predominantly expressed in pancreatic tissue, highlighting organ-specific functions and signaling pathways. BCAM dysregulation or mutation has been linked to several cancers, affecting tumor growth and metastasis, making anti-BCAM antibody (D-6) an invaluable research tool for studying cell adhesion mechanisms and their implications in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
BCAM Antibody (D-6) References:
- Novel epinephrine and cyclic AMP-mediated activation of BCAM/Lu-dependent sickle (SS) RBC adhesion. | Hines, PC., et al. 2003. Blood. 101: 3281-7. PMID: 12506027
- Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. | Zhang, H., et al. 2003. Nat Biotechnol. 21: 660-6. PMID: 12754519
- Role of Rap1 in promoting sickle red blood cell adhesion to laminin via BCAM/LU. | Murphy, MM., et al. 2005. Blood. 105: 3322-9. PMID: 15613546
- The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. | Parsons, SF., et al. 1995. Proc Natl Acad Sci U S A. 92: 5496-500. PMID: 7777537
- Molecular cloning of the B-CAM cell surface glycoprotein of epithelial cancers: a novel member of the immunoglobulin superfamily. | Campbell, IG., et al. 1994. Cancer Res. 54: 5761-5. PMID: 7954395
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
BCAM Antibody (D-6) | sc-365191 | 200 µg/ml | $316.00 | |||
BCAM Antibody (D-6): m-IgGκ BP-HRP Bundle | sc-522157 | 200 µg Ab, 40 µg BP | $354.00 | |||
BCAM Antibody (D-6): m-IgG2b BP-HRP Bundle | sc-549005 | 200 µg Ab; 10 µg BP | $354.00 | |||
BCAM Antibody (D-6) AC | sc-365191 AC | 500 µg/ml, 25% agarose | $416.00 | |||
BCAM Antibody (D-6) HRP | sc-365191 HRP | 200 µg/ml | $316.00 | |||
BCAM Antibody (D-6) FITC | sc-365191 FITC | 200 µg/ml | $330.00 | |||
BCAM Antibody (D-6) PE | sc-365191 PE | 200 µg/ml | $343.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 488 | sc-365191 AF488 | 200 µg/ml | $357.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 546 | sc-365191 AF546 | 200 µg/ml | $357.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 594 | sc-365191 AF594 | 200 µg/ml | $357.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 647 | sc-365191 AF647 | 200 µg/ml | $357.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 680 | sc-365191 AF680 | 200 µg/ml | $357.00 | |||
BCAM Antibody (D-6) Alexa Fluor® 790 | sc-365191 AF790 | 200 µg/ml | $357.00 |