Anti-BBOX1 Antibody (E-11) is a mouse monoclonal IgG1 (kappa light chain) BBOX1 antibody provided at 200 µg/ml
raised against amino acids 47-346 mapping within an internal region of BBOX1 of human origin
BBOX1 Antibody (E-11) is recommended for detection of BBOX1 of human origin by WB, IP, IF, IHC(P) and ELISA
Anti-BBOX1 Antibody (E-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
See m-IgGκ BP-HRP (mouse IgGκ binding protein-HRP), our highly recommended recombinant alternative to conventional secondary anti-mouse IgG reagents.
Contact our Technical Service Department (or your local Distributor) for more information on how to receive a FREE 10 µg sample of BBOX1 (E-11): sc-373774.
Every item is shipped based on the best shipping method assessed for the temperature requirements of that specific item. Items are grouped and shipped together whenever
possible, and a separate shipping charge will be included for each shipping method required. Shipping charges listed below are from our US warehouses to the Contiguous US,
Alaska, Hawaii, Canada and Puerto Rico. Shipping charges for countries outside the US and Canada will be determined once order has been received
Please note: We can not ship to PO boxes
Express Blue Ice
Express Dry Ice
Animal Health Prescription Item
SHIPPING METHODS & CHARGES
Ships via FedEx Ground to Contiguous US, Alaska, Canada, Monday through Friday. This method is used for less temperature sensitive items such as lab ware and animal
health products, bulky and/or heavy items
Labware ships FedEx Ground free of charge to the contiguous US
BBOX1 Antibody (E-11) is a high quality monoclonal BBOX1 antibody (also designated BBOX1 antibody) suitable for the detection of the BBOX1 protein of human origin. BBOX1 Antibody (E-11) is available as both the non-conjugated anti-BBOX1 antibody form, as well as multiple conjugated forms of anti-BBOX1 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. BBOX1 (butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1), also known as BBH, BBOX, G-BBH (gamma-butyrobetaine hydroxylase) or γ-BBH, is a member of the γ-BBH/TMLD family of proteins. Localizing to the cytoplasm and predominantly expressed in kidney, BBOX1 plays a role in the biosynthesis of amines, polyamines and carnitines. More specifically, BBOX1 catalyzes the hydroxylation of γ-butyrobetaine to L-carnitine, a reaction that requires iron and ascorbate as cofactors. This is the last of five steps comprising the L-carnitine biosynthesis pathway and it is important for the proper transport of activated fatty acids across the mitochondrial membrane. Coupled to this reaction, BBOX1 simultaneously catalyzes the oxidative decarboxylation of α-ketoglutarate to succinate.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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