ATP5E Antibody (A-12): sc-393696

ATP5E Antibody (A-12) is a mouse monoclonal IgG2b antibody that detects mitochondrial ATPase ε chain (ATP5E) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ATP5E plays a crucial role in cellular energy metabolism by catalyzing the synthesis of adenosine triphosphate (ATP) in the mitochondria, which is essential for various biochemical processes that sustain life. ATP5E is located in the mitochondrial inner membrane, where ATP5E forms part of the ATP synthase complex, a vital component for converting the energy stored in proton gradients into ATP. This localization ensures ATP production remains closely linked to mitochondrial function and overall cellular energy status. The structure of ATP5E, which includes a small ε chain composed of 50 amino acids, is integral to the assembly and stability of the ATP synthase complex, influencing ATP production efficiency. Anti-ATP5E antibody (A-12) serves as an invaluable tool for researchers studying mitochondrial function, energy metabolism, and related pathologies, providing insights into mechanisms underlying various diseases associated with mitochondrial dysfunction.

The preferred ATP5E antibody is ATP5E Antibody (A-11): sc-393695.