Date published: 2026-5-15

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ASIC4 Antibody (D-3): sc-377063

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Datasheets
  • ASIC4 Antibody (D-3) is a mouse monoclonal IgG2b κ provided at 200 µg/ml
  • raised against amino acids 246-325 mapping within an internal region of ASIC4 of human origin
  • recommended for detection of ASIC4 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA; also reactive with additional species, including and equine, canine, bovine and porcine
  • m-IgG Fc BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ASIC4 Antibody (D-3) for WB and IHC(P) applications. These reagents are now offered in bundles with ASIC4 Antibody (D-3) (see ordering information below).
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    ASIC4 Antibody (D-3) is a mouse monoclonal IgG2b antibody that detects ASIC4 in mouse, rat, and human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA). ASIC4, also known as ACCN4 and BNAC4, is a member of the acid-sensing ion channel family and plays a crucial role in detecting pH changes, particularly in the pituitary gland and inner ear, where ASIC4 is abundantly expressed. ASIC4′s localization in these tissues suggests involvement in physiological processes such as hormone secretion and sensory perception, which are vital for maintaining homeostasis and responding to environmental stimuli. Additionally, ASIC4′s interaction with other proteins in the ASIC family, such as ASIC1 and ASIC2, highlights a potential role in modulating neuronal excitability and pain sensation, making ASIC4 an important target for research in neurobiology and pain management. Anti-ASIC4 antibody (D-3) is an essential tool for researchers exploring functional dynamics in various biological contexts.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    ASIC4 Antibody (D-3)

    sc-377063
    200 µg/ml
    $322.00

    ASIC4 Antibody (D-3): m-IgG Fc BP-HRP Bundle

    sc-538020
    200 µg Ab; 10 µg BP
    $361.00

    ASIC4 Antibody (D-3): m-IgGκ BP-HRP Bundle

    sc-535540
    200 µg Ab; 40 µg BP
    $361.00

    Can ASIC4 (D-3): sc-377063 monoclonal antibody be used to stain formalin-fixed, paraffin-embedded (FFPE) tissue sections?

    Asked by: AbPolly
    Thank you for your question. Yes, ASIC4 (D-3): sc-377063 has been validated for use in IHC with paraffin-embedded sections. We recommend performing antigen retrieval with sodium citrate buffer (pH 6) and heat. The full protocol can be found here: https://www.scbt.com/scbt/resources/protocols/immunoperoxidase-staining
    Answered by: Technical Support
    Date published: 2017-02-27
    • y_2026, m_5, d_14, h_12CST
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    Rated 5 out of 5 by from Beautiful immunoperoxidase cytoplasmic stainingBeautiful immunoperoxidase cytoplasmic staining in formalin fixed, paraffin-embedded human cerebral cortex tissue. -SCBT QC
    Date published: 2015-04-09
    Rated 5 out of 5 by from Produced positive Western Blot data of ASIC4Produced positive Western Blot data of ASIC4 expression in non-transfected and human ASIC4 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-07-29
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    ASIC4 Antibody (D-3) is rated 5.0 out of 5 by 2.
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