ARRDC1 Antibody (E-6): sc-398652
- ARRDC1 Antibody (E-6) is a mouse monoclonal IgG1 κ ARRDC1 antibody, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 1-98 mapping at the N-terminus of ARRDC1 of human origin
- ARRDC1 Antibody (E-6) is recommended for detection of ARRDC1 of human origin by WB, IP, IF and ELISA
- Anti-ARRDC1 Antibody (E-6) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ARRDC1 Antibody (E-6) for WB applications. These reagents are now offered in bundles with ARRDC1 Antibody (E-6) (see ordering information below).
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ARRDC1 Antibody (E-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARRDC1 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARRDC1 (E-6) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates, providing versatility for different experimental needs. ARRDC1 plays a crucial role in regulating cellular processes, particularly in the endocytic pathway, where ARRDC1 is involved in sorting and trafficking membrane proteins. This function is vital for maintaining cellular homeostasis and signaling, as improper trafficking can lead to various diseases, including cancer and neurodegenerative disorders. ARRDC1 is part of a larger family of arrestin domain-containing proteins, encoded by genes located on human chromosomes 9, 15, and 19. Chromosome 9, where ARRDC1 gene is situated, is significant not only for its size—comprising 4% of the human genome—but also for its association with hereditary hemorrhagic telangiectasia and familial dysautonomia. The intricate interplay of ARRDC1 with other proteins in the endocytic pathway underscores its importance in cellular function and disease mechanisms, making anti-ARRDC1 antibody (E-6) an essential tool for researchers studying these critical biological processes.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ARRDC1 Antibody (E-6) References:
- Agonist-induced internalization of the platelet-activating factor receptor is dependent on arrestins but independent of G-protein activation. Role of the C terminus and the (D/N)PXXY motif. | Chen, Z., et al. 2002. J Biol Chem. 277: 7356-62. PMID: 11729201
- Analysis of candidate genes on chromosome 19 in coeliac disease: an association study of the KIR and LILR gene clusters. | Moodie, SJ., et al. 2002. Eur J Immunogenet. 29: 287-91. PMID: 12121272
- Molecular epigenetics of Angelman syndrome. | Lalande, M. and Calciano, MA. 2007. Cell Mol Life Sci. 64: 947-60. PMID: 17347796
- [The Prader-Willi syndrome]. | Diene, G., et al. 2007. Ann Endocrinol (Paris). 68: 129-37. PMID: 17499572
- Phenotypic and cytogenetic spectrum of 9p trisomy. | Temtamy, SA., et al. 2007. Genet Couns. 18: 29-48. PMID: 17515299
- An anomalous haplotype distribution of the arrestin domain-containing 4 gene (ARRDC4) haplotypes in Caucasians. | Knoll, B., et al. 2008. Genet Test. 12: 147-52. PMID: 18307387
- Characterization of dominant negative arrestins that inhibit beta2-adrenergic receptor internalization by distinct mechanisms. | Orsini, MJ. and Benovic, JL. 1998. J Biol Chem. 273: 34616-22. PMID: 9852134
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARRDC1 Antibody (E-6) | sc-398652 | 200 µg/ml | $316.00 | |||
ARRDC1 Antibody (E-6): m-IgG Fc BP-HRP Bundle | sc-530890 | 200 µg Ab; 10 µg BP | $354.00 | |||
ARRDC1 Antibody (E-6): m-IgGκ BP-HRP Bundle | sc-524441 | 200 µg Ab, 40 µg BP | $354.00 | |||
ARRDC1 Antibody (E-6): m-IgG1 BP-HRP Bundle | sc-544300 | 200 µg Ab; 20 µg BP | $354.00 | |||
ARRDC1 Antibody (E-6) AC | sc-398652 AC | 500 µg/ml, 25% agarose | $416.00 | |||
ARRDC1 Antibody (E-6) HRP | sc-398652 HRP | 200 µg/ml | $316.00 | |||
ARRDC1 Antibody (E-6) FITC | sc-398652 FITC | 200 µg/ml | $330.00 | |||
ARRDC1 Antibody (E-6) PE | sc-398652 PE | 200 µg/ml | $343.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 488 | sc-398652 AF488 | 200 µg/ml | $357.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 546 | sc-398652 AF546 | 200 µg/ml | $357.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 594 | sc-398652 AF594 | 200 µg/ml | $357.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 647 | sc-398652 AF647 | 200 µg/ml | $357.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 680 | sc-398652 AF680 | 200 µg/ml | $357.00 | |||
ARRDC1 Antibody (E-6) Alexa Fluor® 790 | sc-398652 AF790 | 200 µg/ml | $357.00 |