ARL5A/5B/5C Antibody (D-7): sc-390269

ARL5A/5B/5C Antibody (D-7) is a mouse monoclonal IgG1 kappa light chain antibody that detects ARL5A/5B/5C of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ARL5A/5B/5C (D-7) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ARL5A/5B/5C proteins are part of the ADP-ribosylation factor (ARF) family, which are highly conserved guanine nucleotide-binding proteins crucial for eukaryotic vesicular trafficking pathways. ARL5A, also known as ADP-ribosylation factor-like protein 5, is localized to the nucleus and plays a significant role in nuclear dynamics and embryonic development signaling cascades. ARL5A has been shown to interact with heterochromatin protein 1 alpha (HP1α), suggesting involvement in chromatin organization and gene regulation during development. ARL5B, closely related to ARL5A, shares 80% sequence identity and is expressed in various tissues, including brain, heart, lung, cartilage, and kidney, but is absent in spleen. Understanding ARL5A and ARL5B functions and interactions is essential for elucidating roles in cellular processes and potential implications in developmental biology and disease.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-ARL5A/5B/5C Antibody (D-7) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-ARL5A/5B/5C Antibody (D-7) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

ARL5A/5B/5C Antibody (D-7) Specifications

Alternate Product Name: ARL5A/5B/5C

Product Clone Name: D-7

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 1-113

Epitope Target: ARL5B

Epitope Species: human

Product Reactivity/Detection: ARL5A, ARL5B and ARL5C

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for ARL5A/5B/5C Antibody (D-7): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin

The preferred ARL5B antibody is ARL5B Antibody (E-3): sc-393511.