Arginase 2/ARG2 Antibody (C-3): sc-374420
- Arginase 2/ARG2 Antibody (C-3) is a mouse monoclonal IgG2b κ, cited in 2 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 67-105 within an internal region of Arg2 of mouse origin
- Anti-Arginase 2/ARG2 Antibody (C-3) is recommended for detection of Arg2 of mouse and rat origin by WB, IP, IF and ELISA
- Anti-Arginase 2/ARG2 Antibody (C-3) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP is the preferred secondary detection reagent for Arginase 2/ARG2 Antibody (C-3) for WB applications. This reagent is now offered in a bundle with Arginase 2/ARG2 Antibody (C-3) (see ordering information below).
QUICK LINKS
Arg2 Antibody (C-3) is a mouse monoclonal IgG2b kappa light chain antibody that specifically targets an epitope within amino acids 67–105 of mouse Arginase 2 (ARG2). Arginase 2, also known as Type II Arginase, is a mitochondrial enzyme that catalyzes the hydrolysis of L-arginine into L-ornithine and urea, playing a crucial role in the urea cycle and polyamine biosynthesis. Unlike its cytosolic counterpart Arginase 1, which is predominantly expressed in the liver, ARG2 is primarily located in the mitochondria of extrahepatic tissues such as the kidney and small intestine. The mitochondrial localization of ARG2 regulates the availability of L-arginine within mitochondria, influencing nitric oxide production and thus affecting vascular function and immune responses. Dysregulation of ARG2 expression has been implicated in various pathological conditions, including cardiovascular diseases, neurodegenerative disorders, and cancer, highlighting ARG2′s importance in cellular metabolism and disease mechanisms. ARG2 (C-3) monoclonal antibody demonstrates reactivity with mouse and rat ARG2 in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA), making ARG2 (C-3) antibody a valuable tool for researchers studying ARG2 function and localization. Anti-ARG2 antibody (C-3) enables precise detection and analysis of ARG2, advancing our understanding of ARG2′s role in physiological and pathological processes. ARG2 (C-3) monoclonal antibody provides high specificity and affinity for investigations into nitric oxide synthesis regulation and ARG2 activity in health and disease.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Arginase 2/ARG2 Antibody (C-3) | sc-374420 | 200 µg/ml | $322.00 | |||
Arg2 Antibody (C-3): m-IgG Fc BP-HRP Bundle | sc-525962 | 200 µg Ab; 10 µg BP | $361.00 | |||
Arg2 Antibody (C-3) AC | sc-374420 AC | 500 µg/ml, 25% agarose | $424.00 | |||
Arg2 Antibody (C-3) HRP | sc-374420 HRP | 200 µg/ml | $322.00 | |||
Arg2 Antibody (C-3) FITC | sc-374420 FITC | 200 µg/ml | $336.00 | |||
Arg2 Antibody (C-3) PE | sc-374420 PE | 200 µg/ml | $349.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 488 | sc-374420 AF488 | 200 µg/ml | $364.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 546 | sc-374420 AF546 | 200 µg/ml | $364.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 594 | sc-374420 AF594 | 200 µg/ml | $364.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 647 | sc-374420 AF647 | 200 µg/ml | $364.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 680 | sc-374420 AF680 | 200 µg/ml | $364.00 | |||
Arg2 Antibody (C-3) Alexa Fluor® 790 | sc-374420 AF790 | 200 µg/ml | $364.00 | |||
Arg2 (C-3) Neutralizing Peptide | sc-374420 P | 100 µg/0.5 ml | $69.00 |