ARA54 Antibody (B-1): sc-376285
- ARA54 Antibody (B-1) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 423-459 near the C-terminus of ARA54 of human origin
- recommended for detection of ARA54 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- TransCruz reagent for ChIP application (sc-376285 X, 200 µg/0.1 ml)
- m-IgG1 BP-HRP is the preferred secondary detection reagent for ARA54 Antibody (B-1) for WB and IHC(P) applications. This reagent is now offered in a bundle with ARA54 Antibody (B-1) (see ordering information below).
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ARA54 Antibody (B-1) is a mouse monoclonal IgG1 antibody that detects ARA54 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). ARA54 plays a crucial role as a coactivator of the androgen receptor (AR), which is essential for mediating the effects of androgens like testosterone and dihydrotestosterone on male reproductive physiology and phenotype. ARA54 is predominantly located in the nucleus, where ARA54 interacts with AR to enhance transcriptional activity, thereby influencing gene expression related to male development and function. This nuclear localization allows ARA54 to effectively modulate AR signaling pathways, which are critical for processes such as spermatogenesis and the maintenance of male secondary sexual characteristics. Additionally, ARA54 contains a RING finger domain that is implicated in protein-protein interactions, further underscoring ARA54′s importance in the regulation of AR activity and the broader context of steroid hormone signaling.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ARA54 Antibody (B-1) | sc-376285 | 200 µg/ml | $322.00 | |||
ARA54 Antibody (B-1): m-IgG1 BP-HRP Bundle | sc-542701 | 200 µg Ab; 20 µg BP | $361.00 | |||
ARA54 (B-1) Neutralizing Peptide | sc-376285 P | 100 µg/0.5 ml | $69.00 | |||
ARA54 Antibody (B-1) X | sc-376285 X | 200 µg/0.1 ml | $322.00 |