apoF Antibody (B-6): sc-398151

apoF Antibody (B-6) is a mouse monoclonal IgG1 kappa light chain antibody that detects apoF protein of mouse origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). anti-apoF antibody (B-6) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. Apolipoproteins, such as apoF (also known as lipid transfer inhibitor protein or LTIP), play a crucial role in lipid metabolism by facilitating the transport of fats in the bloodstream as part of lipoproteins. apoF (B-6) monoclonal antibody recognizes a 308 amino acid secreted protein primarily expressed in liver tissues and found in plasma, where apoF functions to inhibit the activity of cholesteryl ester transfer protein (CETP). This inhibition is vital for regulating cholesterol transport, which is essential for maintaining lipid homeostasis and preventing cardiovascular diseases. The gene encoding apoF is located on human chromosome 12, a region associated with various genetic disorders, including hypochondrogenesis and Noonan syndrome, highlighting the importance of apoF in both health and disease.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

apoF Antibody (B-6) References:

1. Lipid transfer inhibitor protein defines the participation of high density lipoprotein subfractions in lipid transfer reactions mediated by cholesterol ester transfer protein (CETP).  |  Paromov, VM. and Morton, RE. 2003. J Biol Chem. 278: 40859-66. PMID: 12907677
2. Lipid transfer inhibitor protein (apolipoprotein F) concentration in normolipidemic and hyperlipidemic subjects.  |  Morton, RE., et al. 2008. J Lipid Res. 49: 127-35. PMID: 17901467
3. Control of cholesteryl ester transfer protein activity by sequestration of lipid transfer inhibitor protein in an inactive complex.  |  He, Y., et al. 2008. J Lipid Res. 49: 1529-37. PMID: 18369235
4. Isolation and partial characterization of a new acidic apolipoprotein (apolipoprotein F) from high density lipoproteins of human plasma.  |  Olofsson, SO., et al. 1978. Biochemistry. 17: 1032-6. PMID: 204339
5. Isolation and characterization of simple and complex lipoproteins containing apolipoprotein F from human plasma.  |  Koren, E., et al. 1982. Biochemistry. 21: 5347-51. PMID: 6816269
6. Purification and molecular cloning of human apolipoprotein F.  |  Day, JR., et al. 1994. Biochem Biophys Res Commun. 203: 1146-51. PMID: 8093033
7. Molecular cloning and expression of lipid transfer inhibitor protein reveals its identity with apolipoprotein F.  |  Wang, X., et al. 1999. J Biol Chem. 274: 1814-20. PMID: 9880564

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-apoF Antibody (B-6) has 0 citations in a variety of scientific publications.

Primary antibodies like Anti-apoF Antibody (B-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

apoF Antibody (B-6) Specifications

Alternate Product Name: apoF

Product Clone Name: B-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 44-326

Epitope Target: apoF

Epitope Species: mouse

Product Reactivity/Detection: apoF

Species Reactivity/Detection: mouse

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for apoF Antibody (B-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, PE: Phycoerythrin