apolipoprotein E/apoE Antibody (H-4): sc-393774
- apolipoprotein E/apoE Antibody (H-4) is a mouse monoclonal IgG1 κ provided at 200 µg/ml
- specific for an epitope mapping between amino acids 293-301 at the C-terminus of apoE of rat origin
- recommended for detection of apoE of mouse and rat origin by WB, IP, IF, IHC(P) and ELISA
- See apolipoprotein E/apoE (F-9): sc-390925 for apolipoprotein E/apoE antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for apolipoprotein E/apoE Antibody (H-4) for WB and IHC(P) applications. These reagents are now offered in bundles with apolipoprotein E/apoE Antibody (H-4) (see ordering information below).
apoE Antibody (H-4) is a mouse monoclonal IgG1 kappa light chain antibody that specifically recognizes an epitope located between amino acids 293-301 at the C-terminus of apolipoprotein E (apoE) from rat, with reactivity to mouse and rat samples. Apolipoprotein E (apoE) plays a critical role in lipid transport and metabolism by binding, internalizing, and mediating the degradation of lipoprotein particles. ApoE as a ligand for receptors like the LDL receptor and the hepatic apoE receptor is essential for removing cholesterol and other lipids from the bloodstream, which is vital for maintaining cardiovascular health and preventing atherosclerosis. ApoE is present in various plasma lipoprotein fractions, including VLDL and HDL, and is produced in multiple organs, contributing to systemic lipid regulation. ApoE exists in three major isoforms, E2, E3, and E4, which influence lipid metabolism, with E4 being particularly associated with increased risk for neurodegenerative diseases. Anti-apoE antibody (H-4) is validated for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA), making this tool invaluable for researchers investigating apoE functions in lipid homeostasis and disease mechanisms.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apolipoprotein E/apoE Antibody (H-4) | sc-393774 | 200 µg/ml | $316.00 | |||
apolipoprotein E/apoE Antibody (H-4): m-IgG Fc BP-HRP Bundle | sc-538308 | 200 µg Ab; 10 µg BP | $354.00 | |||
apolipoprotein E/apoE Antibody (H-4): m-IgGκ BP-HRP Bundle | sc-535890 | 200 µg Ab; 40 µg BP | $354.00 | |||
apolipoprotein E/apoE Antibody (H-4): m-IgG1 BP-HRP Bundle | sc-545631 | 200 µg Ab; 20 µg BP | $354.00 | |||
apolipoprotein E/apoE (H-4) Neutralizing Peptide | sc-393774 P | 100 µg/0.5 ml | $68.00 |