apolipoprotein E/apoE Antibody (F-9): sc-390925
- apolipoprotein E/apoE Antibody (F-9) is a mouse monoclonal IgG2a κ, cited in 22 publications, provided at 200 µg/ml
- raised against amino acids 31-253 mapping within an internal region of apoE of human origin
- Anti-apolipoprotein E/apoE Antibody (F-9) is recommended for detection of apoE of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- Anti-apolipoprotein E/apoE Antibody (F-9) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for apolipoprotein E/apoE Antibody (F-9) for WB and IHC(P) applications. These reagents are now offered in bundles with apolipoprotein E/apoE Antibody (F-9) (see ordering information below).
apoE Antibody (F-9) is a mouse monoclonal IgG2a kappa light chain antibody that targets apolipoprotein E (apoE), specifically recognizing amino acids 31-253 within its internal region in human, mouse, and rat samples. Apolipoprotein E (apoE) is a vital component of plasma lipoproteins involved in lipid transport and cholesterol metabolism. Structurally, apoE is composed of two major domains: the N-terminal domain responsible for receptor binding and the C-terminal domain important for lipid binding, which allows apoE to efficiently mediate lipid transport between cells. This structure is crucial for apoE′s function, as any alterations can affect binding affinity for lipoprotein receptors, such as the LDL receptor, influencing cholesterol clearance from the bloodstream. Additionally, the structural diversity of apoE isoforms (E2, E3, and E4) contributes to varying functional outcomes, particularly in lipid metabolism and neurodegenerative diseases. anti-apoE antibody (F-9) is validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and enzyme-linked immunosorbent assay (ELISA), making anti-apoE antibody (F-9) an essential tool for researchers investigating the structural and functional roles of apoE in lipid metabolism and associated pathologies.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
apolipoprotein E/apoE Antibody (F-9) | sc-390925 | 200 µg/ml | $316.00 | |||
apolipoprotein E/apoE Antibody (F-9): m-IgGκ BP-HRP Bundle | sc-523736 | 200 µg Ab, 40 µg BP | $354.00 | |||
apolipoprotein E/apoE Antibody (F-9): m-IgG2a BP-HRP Bundle | sc-546167 | 200 µg Ab; 10 µg BP | $354.00 | |||
apolipoprotein E/apoE Antibody (F-9) AC | sc-390925 AC | 500 µg/ml, 25% agarose | $416.00 | |||
apolipoprotein E/apoE Antibody (F-9) HRP | sc-390925 HRP | 200 µg/ml | $316.00 | |||
apolipoprotein E/apoE Antibody (F-9) FITC | sc-390925 FITC | 200 µg/ml | $330.00 | |||
apolipoprotein E/apoE Antibody (F-9) PE | sc-390925 PE | 200 µg/ml | $343.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 488 | sc-390925 AF488 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 546 | sc-390925 AF546 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 594 | sc-390925 AF594 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 647 | sc-390925 AF647 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 680 | sc-390925 AF680 | 200 µg/ml | $357.00 | |||
apolipoprotein E/apoE Antibody (F-9) Alexa Fluor® 790 | sc-390925 AF790 | 200 µg/ml | $357.00 |