Apg-1 Antibody (C-6): sc-137027
- Apg-1 Antibody (C-6) is a mouse monoclonal IgG1 κ, cited in 1 publications, provided at 200 µg/ml
- raised against amino acids 96-582 of Apg-1 of mouse origin
- recommended for detection of Apg-1 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA
- m-IgG Fc BP-HRP, m-IgG1 BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for Apg-1 Antibody (C-6) for WB and IHC(P) applications. These reagents are now offered in bundles with Apg-1 Antibody (C-6) (see ordering information below).
Apg-1 Antibody (C-6) is a mouse monoclonal IgG1 antibody that detects Apg-1 in mouse, rat, and human samples through various applications including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry, and enzyme-linked immunosorbent assay (ELISA). Apg-1, also known as HSPA4L or osmotic stress protein 94, is an 839 amino acid protein that plays a crucial role as a molecular chaperone, facilitating proper protein folding and preventing aggregation, which is vital for maintaining cellular homeostasis under stress conditions. Anti-Apg-1 antibody (C-6) recognizes a protein primarily located in the cytoplasm and nucleus, with nuclear translocation following heat shock highlighting its importance in cellular stress responses and gene expression regulation. Apg-1 (C-6) antibody provides reliable detection and characterization of this essential protein, making it valuable for researchers studying stress response mechanisms and related pathways in various biological contexts.
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Apg-1 Antibody (C-6) References:
- Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes. | Nonoguchi, K., et al. 1999. Gene. 237: 21-8. PMID: 10524232
- Tor-mediated induction of autophagy via an Apg1 protein kinase complex. | Kamada, Y., et al. 2000. J Cell Biol. 150: 1507-13. PMID: 10995454
- Chemical genetic analysis of Apg1 reveals a non-kinase role in the induction of autophagy. | Abeliovich, H., et al. 2003. Mol Biol Cell. 14: 477-90. PMID: 12589048
- Glycolipid expression in prostatic tissue and analysis of the antigen recognized by antiprostatic monoclonal antibody APG1. | Satoh, M., et al. 1992. Urol Int. 48: 20-4. PMID: 1376009
- Regulation of expression of the stress response gene, Osp94: identification of the tonicity response element and intracellular signalling pathways. | Kojima, R., et al. 2004. Biochem J. 380: 783-94. PMID: 15018608
- Hspa4l-deficient mice display increased incidence of male infertility and hydronephrosis development. | Held, T., et al. 2006. Mol Cell Biol. 26: 8099-108. PMID: 16923965
- Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice. | Mohamed, BA., et al. 2014. Am J Respir Cell Mol Biol. 50: 817-24. PMID: 23980576
- Novel function of the C-terminal region of the Hsp110 family member Osp94 in unfolded protein refolding. | Kojima, R., et al. 2022. J Cell Sci. 135: PMID: 35237814
- A novel hsp110-related gene, apg-1, that is abundantly expressed in the testis responds to a low temperature heat shock rather than the traditional elevated temperatures. | Kaneko, Y., et al. 1997. J Biol Chem. 272: 2640-5. PMID: 9006898
- Developmentally regulated expression of APG-1, a member of heat shock protein 110 family in murine male germ cells. | Kaneko, Y., et al. 1997. Biochem Biophys Res Commun. 233: 113-6. PMID: 9144406
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Apg-1 Antibody (C-6) | sc-137027 | 200 µg/ml | $322.00 | |||
Apg-1 Antibody (C-6): m-IgG Fc BP-HRP Bundle | sc-537390 | 200 µg Ab; 10 µg BP | $361.00 | |||
Apg-1 Antibody (C-6): m-IgGκ BP-HRP Bundle | sc-534643 | 200 µg Ab; 40 µg BP | $361.00 | |||
Apg-1 Antibody (C-6): m-IgG1 BP-HRP Bundle | sc-545170 | 200 µg Ab; 20 µg BP | $361.00 |